STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pdap128 kDa heat- and acid-stable phosphoprotein; Belongs to the PDAP1 family. (181 aa)    
Predicted Functional Partners:
Rfx8
RFX family member 8, lacking RFX DNA-binding domain.
      
 0.670
Tex45
Similar to FLJ35784 protein (Predicted).
      
 0.660
Pdgfa
Platelet-derived growth factor subunit A; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by t [...]
   
 
 0.659
Rmnd1
Required for meiotic nuclear division 1 homolog.
   
  
 0.599
Trappc5
Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
   
  
 0.588
Dtymk
Deoxythymidylate kinase (Predicted), isoform CRA_b.
   
  
 0.505
Mtch1
Mitochondrial carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.484
Cdc42bpg
CDC42 binding protein kinase gamma (DMPK-like) (Predicted); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
      
 0.476
Rpp40
Ribonuclease P protein subunit p40; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
   
  
 0.471
Pex11g
Peroxisomal biogenesis factor 11c (Predicted), isoform CRA_b.
   
  
 0.464
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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