node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amfr | Aup1 | ENSRNOP00000072893 | ENSRNOP00000010602 | Autocrine motility factor receptor. | Ancient ubiquitous protein 1; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. | 0.653 |
Amfr | Rnf139 | ENSRNOP00000072893 | ENSRNOP00000067352 | Autocrine motility factor receptor. | Ring finger protein 139. | 0.803 |
Amfr | Syvn1 | ENSRNOP00000072893 | ENSRNOP00000028462 | Autocrine motility factor receptor. | Synovial apoptosis inhibitor 1, synoviolin, isoform CRA_b. | 0.832 |
Amfr | Ubc | ENSRNOP00000072893 | ENSRNOP00000074688 | Autocrine motility factor receptor. | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.871 |
Amfr | Ube2g1 | ENSRNOP00000072893 | ENSRNOP00000013486 | Autocrine motility factor receptor. | Ubiquitin-conjugating enzyme E2 G1, N-terminally processed; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4; Belongs to the ubiquitin-conjugating enzyme family. | 0.663 |
Amfr | Ube2g2 | ENSRNOP00000072893 | ENSRNOP00000001636 | Autocrine motility factor receptor. | Ubiquitin-conjugating enzyme E2G 2 (Predicted), isoform CRA_b; Belongs to the ubiquitin-conjugating enzyme family. | 0.989 |
Aup1 | Amfr | ENSRNOP00000010602 | ENSRNOP00000072893 | Ancient ubiquitous protein 1; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. | Autocrine motility factor receptor. | 0.653 |
Aup1 | Rbx1 | ENSRNOP00000010602 | ENSRNOP00000069049 | Ancient ubiquitous protein 1; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. | Ring-box 1. | 0.551 |
Aup1 | Rnf139 | ENSRNOP00000010602 | ENSRNOP00000067352 | Ancient ubiquitous protein 1; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. | Ring finger protein 139. | 0.648 |
Aup1 | Syvn1 | ENSRNOP00000010602 | ENSRNOP00000028462 | Ancient ubiquitous protein 1; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. | Synovial apoptosis inhibitor 1, synoviolin, isoform CRA_b. | 0.878 |
Aup1 | Ube2g2 | ENSRNOP00000010602 | ENSRNOP00000001636 | Ancient ubiquitous protein 1; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. | Ubiquitin-conjugating enzyme E2G 2 (Predicted), isoform CRA_b; Belongs to the ubiquitin-conjugating enzyme family. | 0.997 |
Emc3 | Ube2g2 | ENSRNOP00000013488 | ENSRNOP00000001636 | ER membrane protein complex subunit 3; Belongs to the EMC3 family. | Ubiquitin-conjugating enzyme E2G 2 (Predicted), isoform CRA_b; Belongs to the ubiquitin-conjugating enzyme family. | 0.800 |
Rbx1 | Aup1 | ENSRNOP00000069049 | ENSRNOP00000010602 | Ring-box 1. | Ancient ubiquitous protein 1; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. | 0.551 |
Rbx1 | Syvn1 | ENSRNOP00000069049 | ENSRNOP00000028462 | Ring-box 1. | Synovial apoptosis inhibitor 1, synoviolin, isoform CRA_b. | 0.763 |
Rbx1 | Uba1 | ENSRNOP00000069049 | ENSRNOP00000033950 | Ring-box 1. | Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites. | 0.568 |
Rbx1 | Ubc | ENSRNOP00000069049 | ENSRNOP00000074688 | Ring-box 1. | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.886 |
Rbx1 | Ube2g1 | ENSRNOP00000069049 | ENSRNOP00000013486 | Ring-box 1. | Ubiquitin-conjugating enzyme E2 G1, N-terminally processed; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4; Belongs to the ubiquitin-conjugating enzyme family. | 0.747 |
Rbx1 | Ube2g2 | ENSRNOP00000069049 | ENSRNOP00000001636 | Ring-box 1. | Ubiquitin-conjugating enzyme E2G 2 (Predicted), isoform CRA_b; Belongs to the ubiquitin-conjugating enzyme family. | 0.805 |
Rnf139 | Amfr | ENSRNOP00000067352 | ENSRNOP00000072893 | Ring finger protein 139. | Autocrine motility factor receptor. | 0.803 |
Rnf139 | Aup1 | ENSRNOP00000067352 | ENSRNOP00000010602 | Ring finger protein 139. | Ancient ubiquitous protein 1; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. | 0.648 |