node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cnksr1 | Rasl11b | ENSRNOP00000029346 | ENSRNOP00000002869 | Connector enhancer of kinase suppressor of Ras 1. | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | 0.564 |
Cnksr1 | Rassf1 | ENSRNOP00000029346 | ENSRNOP00000030024 | Connector enhancer of kinase suppressor of Ras 1. | Ras association (RalGDS/AF-6) domain family 1, isoform CRA_b. | 0.475 |
Cnksr1 | Syde2 | ENSRNOP00000029346 | ENSRNOP00000031789 | Connector enhancer of kinase suppressor of Ras 1. | Synapse defective Rho GTPase homolog 2. | 0.404 |
Dcdc2b | Rasl11b | ENSRNOP00000065806 | ENSRNOP00000002869 | Doublecortin domain containing 2b. | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | 0.560 |
Itsn1 | Itsn2 | ENSRNOP00000044773 | ENSRNOP00000065329 | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles. Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | Intersectin 2. | 0.618 |
Itsn1 | Rasl11b | ENSRNOP00000044773 | ENSRNOP00000002869 | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles. Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | 0.590 |
Itsn1 | Rhof | ENSRNOP00000044773 | ENSRNOP00000063718 | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles. Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | Ras homolog family member F, filopodia-associated. | 0.798 |
Itsn2 | Itsn1 | ENSRNOP00000065329 | ENSRNOP00000044773 | Intersectin 2. | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles. Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | 0.618 |
Itsn2 | Rasl11b | ENSRNOP00000065329 | ENSRNOP00000002869 | Intersectin 2. | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | 0.667 |
Itsn2 | Rhof | ENSRNOP00000065329 | ENSRNOP00000063718 | Intersectin 2. | Ras homolog family member F, filopodia-associated. | 0.815 |
Lyzl4 | Rasl11b | ENSRNOP00000026173 | ENSRNOP00000002869 | Lysozyme-like protein 4; May be involved in fertilization (By similarity). Has no detectable bacteriolytic and lysozyme activities in vitro. | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | 0.511 |
Rasl11b | Cnksr1 | ENSRNOP00000002869 | ENSRNOP00000029346 | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | Connector enhancer of kinase suppressor of Ras 1. | 0.564 |
Rasl11b | Dcdc2b | ENSRNOP00000002869 | ENSRNOP00000065806 | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | Doublecortin domain containing 2b. | 0.560 |
Rasl11b | Itsn1 | ENSRNOP00000002869 | ENSRNOP00000044773 | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles. Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | 0.590 |
Rasl11b | Itsn2 | ENSRNOP00000002869 | ENSRNOP00000065329 | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | Intersectin 2. | 0.667 |
Rasl11b | Lyzl4 | ENSRNOP00000002869 | ENSRNOP00000026173 | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | Lysozyme-like protein 4; May be involved in fertilization (By similarity). Has no detectable bacteriolytic and lysozyme activities in vitro. | 0.511 |
Rasl11b | Rassf1 | ENSRNOP00000002869 | ENSRNOP00000030024 | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | Ras association (RalGDS/AF-6) domain family 1, isoform CRA_b. | 0.514 |
Rasl11b | Rhof | ENSRNOP00000002869 | ENSRNOP00000063718 | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | Ras homolog family member F, filopodia-associated. | 0.527 |
Rasl11b | Shank1 | ENSRNOP00000002869 | ENSRNOP00000026100 | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | SH3 and multiple ankyrin repeat domains protein 1; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Overexpression promotes maturation of dendritic spines and the enlargement of spine heads via its ability to recruit Homer to postsynaptic sites, and enhances presynaptic function. | 0.515 |
Rasl11b | Shank3 | ENSRNOP00000002869 | ENSRNOP00000071295 | Ras-like protein family member 11B; Belongs to the small GTPase superfamily. Ras family. | SH3 and multiple ankyrin repeat domains protein 3; Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex [...] | 0.500 |