STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MmdMonocyte to macrophage differentiation factor; Is involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion. (238 aa)    
Predicted Functional Partners:
Paqr4
Progestin and adipoQ receptor family member IV.
   
  
 0.685
Paqr3
Progestin and adipoQ receptor family member III.
      
 0.665
Nxpe2
Neurexophilin and PC-esterase domain family, member 2.
   
  
 0.617
Hilpda
Hypoxia-inducible lipid droplet-associated.
      
 0.544
Trmt10a
tRNA methyltransferase 10 homolog A; S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs.
      
 0.536
Stard13
StAR-related lipid transfer domain-containing 13.
      
 0.525
Paqr5
Progestin and adipoQ receptor family member 5.
   
  
 0.500
Paqr9
Progestin and adipoQ receptor family member 9.
      
 0.473
Hmgb3-2
Similar to High mobility group protein 4 (HMG-4) (High mobility group protein 2a) (HMG-2a).
      
 0.445
Hmgb3
Similar to High mobility group protein 4 (HMG-4) (High mobility group protein 2a) (HMG-2a).
      
 0.442
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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