node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fam171b | Gde1 | ENSRNOP00000006504 | ENSRNOP00000064735 | Similar to RIKEN cDNA D430039N05 gene (Predicted), isoform CRA_a. | Glycerophosphodiester phosphodiesterase 1; Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (By similarity). Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways. | 0.424 |
Fam171b | Hypm | ENSRNOP00000006504 | ENSRNOP00000004790 | Similar to RIKEN cDNA D430039N05 gene (Predicted), isoform CRA_a. | Huntingtin-interacting protein M. | 0.781 |
Gde1 | Fam171b | ENSRNOP00000064735 | ENSRNOP00000006504 | Glycerophosphodiester phosphodiesterase 1; Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (By similarity). Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways. | Similar to RIKEN cDNA D430039N05 gene (Predicted), isoform CRA_a. | 0.424 |
Gde1 | Hypm | ENSRNOP00000064735 | ENSRNOP00000004790 | Glycerophosphodiester phosphodiesterase 1; Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (By similarity). Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways. | Huntingtin-interacting protein M. | 0.637 |
Glyr1 | Hypm | ENSRNOP00000004159 | ENSRNOP00000004790 | Putative oxidoreductase GLYR1; Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Facilitates Pol II transcription through nucleosomes. Binds DNA (in vitro). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3). Promotes KDM1B demethylase activity. Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. [...] | Huntingtin-interacting protein M. | 0.529 |
Glyr1 | LOC684444 | ENSRNOP00000004159 | ENSRNOP00000065543 | Putative oxidoreductase GLYR1; Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Facilitates Pol II transcription through nucleosomes. Binds DNA (in vitro). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3). Promotes KDM1B demethylase activity. Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. [...] | Similar to HIStone family member (his-41); Belongs to the histone H2B family. | 0.705 |
H1f7 | Hils1 | ENSRNOP00000046187 | ENSRNOP00000037497 | Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | 0.832 |
H1f7 | Hypm | ENSRNOP00000046187 | ENSRNOP00000004790 | Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. | Huntingtin-interacting protein M. | 0.568 |
Hils1 | H1f7 | ENSRNOP00000037497 | ENSRNOP00000046187 | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. | 0.832 |
Hils1 | Hypm | ENSRNOP00000037497 | ENSRNOP00000004790 | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | Huntingtin-interacting protein M. | 0.636 |
Hypm | Fam171b | ENSRNOP00000004790 | ENSRNOP00000006504 | Huntingtin-interacting protein M. | Similar to RIKEN cDNA D430039N05 gene (Predicted), isoform CRA_a. | 0.781 |
Hypm | Gde1 | ENSRNOP00000004790 | ENSRNOP00000064735 | Huntingtin-interacting protein M. | Glycerophosphodiester phosphodiesterase 1; Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (By similarity). Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways. | 0.637 |
Hypm | Glyr1 | ENSRNOP00000004790 | ENSRNOP00000004159 | Huntingtin-interacting protein M. | Putative oxidoreductase GLYR1; Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation. Facilitates Pol II transcription through nucleosomes. Binds DNA (in vitro). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3). Promotes KDM1B demethylase activity. Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. [...] | 0.529 |
Hypm | H1f7 | ENSRNOP00000004790 | ENSRNOP00000046187 | Huntingtin-interacting protein M. | Testis-specific H1 histone; Essential for normal spermatogenesis and male fertility. Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. | 0.568 |
Hypm | Hils1 | ENSRNOP00000004790 | ENSRNOP00000037497 | Huntingtin-interacting protein M. | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | 0.636 |
Hypm | LOC684444 | ENSRNOP00000004790 | ENSRNOP00000065543 | Huntingtin-interacting protein M. | Similar to HIStone family member (his-41); Belongs to the histone H2B family. | 0.625 |
Hypm | Leo1 | ENSRNOP00000004790 | ENSRNOP00000013510 | Huntingtin-interacting protein M. | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser- 5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox [...] | 0.500 |
Hypm | Mysm1 | ENSRNOP00000004790 | ENSRNOP00000030043 | Huntingtin-interacting protein M. | Myb-like, SWIRM and MPN domains 1. | 0.537 |
Hypm | Scp2d1 | ENSRNOP00000004790 | ENSRNOP00000012524 | Huntingtin-interacting protein M. | Similar to RIKEN cDNA 1700010M22 (Predicted). | 0.514 |
Hypm | Zfp839 | ENSRNOP00000004790 | ENSRNOP00000051456 | Huntingtin-interacting protein M. | Zinc finger protein 839. | 0.503 |