node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC100910446 | Napa | ENSRNOP00000065991 | ENSRNOP00000002044 | Syntaxin-7-like; Belongs to the syntaxin family. | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | 0.901 |
LOC100910446 | Stx16 | ENSRNOP00000065991 | ENSRNOP00000073268 | Syntaxin-7-like; Belongs to the syntaxin family. | Syntaxin 16; Belongs to the syntaxin family. | 0.737 |
LOC100910446 | Stx5 | ENSRNOP00000065991 | ENSRNOP00000025664 | Syntaxin-7-like; Belongs to the syntaxin family. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. | 0.846 |
LOC100910446 | Stx7 | ENSRNOP00000065991 | ENSRNOP00000021318 | Syntaxin-7-like; Belongs to the syntaxin family. | Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). Belongs to the syntaxin family. | 0.900 |
LOC100910446 | Stx8 | ENSRNOP00000065991 | ENSRNOP00000005204 | Syntaxin-7-like; Belongs to the syntaxin family. | Syntaxin-8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis- Golgi membranes to the ER. | 0.999 |
LOC100910446 | Vamp7 | ENSRNOP00000065991 | ENSRNOP00000011065 | Syntaxin-7-like; Belongs to the syntaxin family. | Vesicle-associated membrane protein 7; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocy [...] | 0.994 |
LOC100910446 | Vamp8 | ENSRNOP00000065991 | ENSRNOP00000017301 | Syntaxin-7-like; Belongs to the syntaxin family. | Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex (By similarity). Also required for dense-granule secretion in plat [...] | 0.997 |
LOC100910446 | Vti1a | ENSRNOP00000065991 | ENSRNOP00000058953 | Syntaxin-7-like; Belongs to the syntaxin family. | Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2 (By similarity). May be concerned with increased secretion of cytokines as [...] | 0.984 |
LOC100910446 | Vti1b | ENSRNOP00000065991 | ENSRNOP00000070613 | Syntaxin-7-like; Belongs to the syntaxin family. | Vesicle transport through interaction with t-SNAREs homolog 1B; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. | 0.999 |
LOC100910446 | Ykt6 | ENSRNOP00000065991 | ENSRNOP00000020693 | Syntaxin-7-like; Belongs to the syntaxin family. | Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity; Belongs to the synaptobrevin family. | 0.995 |
Napa | LOC100910446 | ENSRNOP00000002044 | ENSRNOP00000065991 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Syntaxin-7-like; Belongs to the syntaxin family. | 0.901 |
Napa | Stx16 | ENSRNOP00000002044 | ENSRNOP00000073268 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Syntaxin 16; Belongs to the syntaxin family. | 0.962 |
Napa | Stx5 | ENSRNOP00000002044 | ENSRNOP00000025664 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. | 0.995 |
Napa | Stx7 | ENSRNOP00000002044 | ENSRNOP00000021318 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). Belongs to the syntaxin family. | 0.980 |
Napa | Stx8 | ENSRNOP00000002044 | ENSRNOP00000005204 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Syntaxin-8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis- Golgi membranes to the ER. | 0.982 |
Napa | Vamp7 | ENSRNOP00000002044 | ENSRNOP00000011065 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Vesicle-associated membrane protein 7; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocy [...] | 0.990 |
Napa | Vamp8 | ENSRNOP00000002044 | ENSRNOP00000017301 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex (By similarity). Also required for dense-granule secretion in plat [...] | 0.990 |
Napa | Vti1a | ENSRNOP00000002044 | ENSRNOP00000058953 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2 (By similarity). May be concerned with increased secretion of cytokines as [...] | 0.978 |
Napa | Vti1b | ENSRNOP00000002044 | ENSRNOP00000070613 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Vesicle transport through interaction with t-SNAREs homolog 1B; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. | 0.985 |
Napa | Ykt6 | ENSRNOP00000002044 | ENSRNOP00000020693 | Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane. | Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity; Belongs to the synaptobrevin family. | 0.973 |