node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Armcx1-2 | Ttc1 | ENSRNOP00000043675 | ENSRNOP00000005304 | Armadillo repeat-containing X-linked protein 1. | Tetratricopeptide repeat domain 1. | 0.553 |
Atp10b | Thg1l | ENSRNOP00000030760 | ENSRNOP00000007917 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | Probable tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis. | 0.611 |
Atp10b | Ttc1 | ENSRNOP00000030760 | ENSRNOP00000005304 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | Tetratricopeptide repeat domain 1. | 0.571 |
Atp10b | Ublcp1 | ENSRNOP00000030760 | ENSRNOP00000006063 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | Ubiquitin-like domain-containing CTD phosphatase 1; Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome (By similarity). | 0.511 |
Enox2 | Ttc1 | ENSRNOP00000050076 | ENSRNOP00000005304 | Ecto-NOX disulfide-thiol exchanger 2. | Tetratricopeptide repeat domain 1. | 0.613 |
Hspa1a | Hspa1b | ENSRNOP00000067749 | ENSRNOP00000075599 | Heat shock 70 kDa protein 1A; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and AD [...] | Heat shock protein family A (Hsp70) member 1B. | 0.732 |
Hspa1a | Hspa4 | ENSRNOP00000067749 | ENSRNOP00000023628 | Heat shock 70 kDa protein 1A; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and AD [...] | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.876 |
Hspa1a | Ttc1 | ENSRNOP00000067749 | ENSRNOP00000005304 | Heat shock 70 kDa protein 1A; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and AD [...] | Tetratricopeptide repeat domain 1. | 0.568 |
Hspa1b | Hspa1a | ENSRNOP00000075599 | ENSRNOP00000067749 | Heat shock protein family A (Hsp70) member 1B. | Heat shock 70 kDa protein 1A; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and AD [...] | 0.732 |
Hspa1b | Hspa4 | ENSRNOP00000075599 | ENSRNOP00000023628 | Heat shock protein family A (Hsp70) member 1B. | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.721 |
Hspa1b | Ttc1 | ENSRNOP00000075599 | ENSRNOP00000005304 | Heat shock protein family A (Hsp70) member 1B. | Tetratricopeptide repeat domain 1. | 0.568 |
Hspa4 | Hspa1a | ENSRNOP00000023628 | ENSRNOP00000067749 | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | Heat shock 70 kDa protein 1A; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and AD [...] | 0.876 |
Hspa4 | Hspa1b | ENSRNOP00000023628 | ENSRNOP00000075599 | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | Heat shock protein family A (Hsp70) member 1B. | 0.721 |
Hspa4 | Ttc1 | ENSRNOP00000023628 | ENSRNOP00000005304 | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | Tetratricopeptide repeat domain 1. | 0.559 |
Ppp1r7 | Ttc1 | ENSRNOP00000022854 | ENSRNOP00000005304 | Protein phosphatase 1 regulatory subunit 7; Regulatory subunit of protein phosphatase 1; Belongs to the SDS22 family. | Tetratricopeptide repeat domain 1. | 0.607 |
Slu7 | Thg1l | ENSRNOP00000005132 | ENSRNOP00000007917 | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family. | Probable tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis. | 0.512 |
Slu7 | Ttc1 | ENSRNOP00000005132 | ENSRNOP00000005304 | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family. | Tetratricopeptide repeat domain 1. | 0.660 |
Slu7 | Ublcp1 | ENSRNOP00000005132 | ENSRNOP00000006063 | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family. | Ubiquitin-like domain-containing CTD phosphatase 1; Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome (By similarity). | 0.414 |
Thg1l | Atp10b | ENSRNOP00000007917 | ENSRNOP00000030760 | Probable tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis. | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. | 0.611 |
Thg1l | Slu7 | ENSRNOP00000007917 | ENSRNOP00000005132 | Probable tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis. | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family. | 0.512 |