Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Appl1 | Gipc1 | ENSRNOP00000018413 | ENSRNOP00000005374 | Adaptor protein, phosphotyrosine-interacting with PH domain and leucine zipper 1. | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | 0.946 |
| Arhgef12 | Gipc1 | ENSRNOP00000074482 | ENSRNOP00000005374 | Rho guanine nucleotide exchange factor 12. | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | 0.746 |
| Arhgef12 | Myo6 | ENSRNOP00000074482 | ENSRNOP00000016428 | Rho guanine nucleotide exchange factor 12. | Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.611 |
| Arhgef12 | Rgs19 | ENSRNOP00000074482 | ENSRNOP00000022451 | Rho guanine nucleotide exchange factor 12. | Regulator of G-protein signaling 19; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein (By similarity). | 0.520 |
| Gipc1 | Appl1 | ENSRNOP00000005374 | ENSRNOP00000018413 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Adaptor protein, phosphotyrosine-interacting with PH domain and leucine zipper 1. | 0.946 |
| Gipc1 | Arhgef12 | ENSRNOP00000005374 | ENSRNOP00000074482 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Rho guanine nucleotide exchange factor 12. | 0.746 |
| Gipc1 | Kdr | ENSRNOP00000005374 | ENSRNOP00000066886 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | 0.781 |
| Gipc1 | Lrp2 | ENSRNOP00000005374 | ENSRNOP00000075159 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium. Endocytosis of leptin in neuronal cells is required for hypothalamic leptin signaling and leptin-mediated r [...] | 0.766 |
| Gipc1 | Myo6 | ENSRNOP00000005374 | ENSRNOP00000016428 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.983 |
| Gipc1 | Nrp1 | ENSRNOP00000005374 | ENSRNOP00000075034 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Neuropilin-1; Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system (By similarity). Mediates the chemorepulsant activity of semaphorins (By similarity). Binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis (By similarity). Binding to VEGFA initiates a signaling pathway needed for motor neuron [...] | 0.975 |
| Gipc1 | Plxnd1 | ENSRNOP00000005374 | ENSRNOP00000033101 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Plexin D1 (Predicted). | 0.977 |
| Gipc1 | Rgs19 | ENSRNOP00000005374 | ENSRNOP00000022451 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Regulator of G-protein signaling 19; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein (By similarity). | 0.982 |
| Gipc1 | Sdc4 | ENSRNOP00000005374 | ENSRNOP00000019386 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Syndecan-4; Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. | 0.833 |
| Gipc1 | Trappc4 | ENSRNOP00000005374 | ENSRNOP00000016145 | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | Trafficking protein particle complex subunit 4; May play a role in vesicular transport from endoplasmic reticulum to Golgi. | 0.754 |
| Kdr | Gipc1 | ENSRNOP00000066886 | ENSRNOP00000005374 | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | 0.781 |
| Kdr | Nrp1 | ENSRNOP00000066886 | ENSRNOP00000075034 | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | Neuropilin-1; Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system (By similarity). Mediates the chemorepulsant activity of semaphorins (By similarity). Binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis (By similarity). Binding to VEGFA initiates a signaling pathway needed for motor neuron [...] | 0.999 |
| Kdr | Plxnd1 | ENSRNOP00000066886 | ENSRNOP00000033101 | Vascular endothelial growth factor receptor 2; Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular grow [...] | Plexin D1 (Predicted). | 0.922 |
| Lrp2 | Gipc1 | ENSRNOP00000075159 | ENSRNOP00000005374 | Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium. Endocytosis of leptin in neuronal cells is required for hypothalamic leptin signaling and leptin-mediated r [...] | PDZ domain-containing protein GIPC1; May be involved in G protein-linked signaling. | 0.766 |
| Lrp2 | Sdc4 | ENSRNOP00000075159 | ENSRNOP00000019386 | Low-density lipoprotein receptor-related protein 2; Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium. Endocytosis of leptin in neuronal cells is required for hypothalamic leptin signaling and leptin-mediated r [...] | Syndecan-4; Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. | 0.454 |
| Myo6 | Arhgef12 | ENSRNOP00000016428 | ENSRNOP00000074482 | Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Rho guanine nucleotide exchange factor 12. | 0.611 |
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