node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cd44 | Cldn7 | ENSRNOP00000009000 | ENSRNOP00000069209 | CD44 antigen. | Claudin-7; Plays a major role in tight junction-specific obliteration of the intercellular space; Belongs to the claudin family. | 0.809 |
Cd44 | Epcam | ENSRNOP00000009000 | ENSRNOP00000021135 | CD44 antigen. | Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. | 0.934 |
Cd44 | Hspa1b | ENSRNOP00000009000 | ENSRNOP00000075599 | CD44 antigen. | Heat shock protein family A (Hsp70) member 1B. | 0.462 |
Cd44 | Hspa4 | ENSRNOP00000009000 | ENSRNOP00000023628 | CD44 antigen. | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.441 |
Cd44 | Icam1 | ENSRNOP00000009000 | ENSRNOP00000028066 | CD44 antigen. | Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. | 0.993 |
Cd44 | Itga4 | ENSRNOP00000009000 | ENSRNOP00000006880 | CD44 antigen. | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. | 0.829 |
Cd44 | Tsg101 | ENSRNOP00000009000 | ENSRNOP00000018194 | CD44 antigen. | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). It may also play a role in the [...] | 0.513 |
Cd44 | Tspan8 | ENSRNOP00000009000 | ENSRNOP00000005909 | CD44 antigen. | Tetraspanin. | 0.703 |
Cldn7 | Cd44 | ENSRNOP00000069209 | ENSRNOP00000009000 | Claudin-7; Plays a major role in tight junction-specific obliteration of the intercellular space; Belongs to the claudin family. | CD44 antigen. | 0.809 |
Cldn7 | Epcam | ENSRNOP00000069209 | ENSRNOP00000021135 | Claudin-7; Plays a major role in tight junction-specific obliteration of the intercellular space; Belongs to the claudin family. | Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. | 0.976 |
Cldn7 | Tspan8 | ENSRNOP00000069209 | ENSRNOP00000005909 | Claudin-7; Plays a major role in tight junction-specific obliteration of the intercellular space; Belongs to the claudin family. | Tetraspanin. | 0.796 |
Epcam | Cd44 | ENSRNOP00000021135 | ENSRNOP00000009000 | Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. | CD44 antigen. | 0.934 |
Epcam | Cldn7 | ENSRNOP00000021135 | ENSRNOP00000069209 | Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. | Claudin-7; Plays a major role in tight junction-specific obliteration of the intercellular space; Belongs to the claudin family. | 0.976 |
Epcam | Icam1 | ENSRNOP00000021135 | ENSRNOP00000028066 | Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. | Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. | 0.458 |
Epcam | Tsg101 | ENSRNOP00000021135 | ENSRNOP00000018194 | Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). It may also play a role in the [...] | 0.590 |
Epcam | Tspan8 | ENSRNOP00000021135 | ENSRNOP00000005909 | Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. | Tetraspanin. | 0.881 |
Hspa1b | Cd44 | ENSRNOP00000075599 | ENSRNOP00000009000 | Heat shock protein family A (Hsp70) member 1B. | CD44 antigen. | 0.462 |
Hspa1b | Hspa4 | ENSRNOP00000075599 | ENSRNOP00000023628 | Heat shock protein family A (Hsp70) member 1B. | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.721 |
Hspa1b | Icam1 | ENSRNOP00000075599 | ENSRNOP00000028066 | Heat shock protein family A (Hsp70) member 1B. | Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. | 0.532 |
Hspa1b | Tsg101 | ENSRNOP00000075599 | ENSRNOP00000018194 | Heat shock protein family A (Hsp70) member 1B. | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). It may also play a role in the [...] | 0.870 |