node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Btg1 | Cnot7 | ENSRNOP00000005910 | ENSRNOP00000016882 | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | CCR4-NOT transcription complex, subunit 7. | 0.701 |
Btg1 | Cnot8 | ENSRNOP00000005910 | ENSRNOP00000003555 | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | CCR4-NOT transcription complex, subunit 8, isoform CRA_a. | 0.668 |
Btg1 | LOC100909849 | ENSRNOP00000005910 | ENSRNOP00000055627 | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | Frizzled-8; Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in [...] | 0.440 |
Btg1 | Prmt1 | ENSRNOP00000005910 | ENSRNOP00000063624 | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | Protein arginine N-methyltransferase 1; Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, ILF3, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15, EWS, HABP4 and SERBP1. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation (By similarity). Methylates H4R3 in genes involved in glioblastomagenesis in a CHTOP- and/or TET1 [...] | 0.638 |
Btg1 | Rnmt | ENSRNOP00000005910 | ENSRNOP00000022410 | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | mRNA cap guanine-N7 methyltransferase; Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'- terminal GpppC; Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family. | 0.474 |
Cnot7 | Btg1 | ENSRNOP00000016882 | ENSRNOP00000005910 | CCR4-NOT transcription complex, subunit 7. | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | 0.701 |
Cnot7 | Cnot8 | ENSRNOP00000016882 | ENSRNOP00000003555 | CCR4-NOT transcription complex, subunit 7. | CCR4-NOT transcription complex, subunit 8, isoform CRA_a. | 0.973 |
Cnot8 | Btg1 | ENSRNOP00000003555 | ENSRNOP00000005910 | CCR4-NOT transcription complex, subunit 8, isoform CRA_a. | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | 0.668 |
Cnot8 | Cnot7 | ENSRNOP00000003555 | ENSRNOP00000016882 | CCR4-NOT transcription complex, subunit 8, isoform CRA_a. | CCR4-NOT transcription complex, subunit 7. | 0.973 |
LOC100909849 | Btg1 | ENSRNOP00000055627 | ENSRNOP00000005910 | Frizzled-8; Receptor for Wnt proteins. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in [...] | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | 0.440 |
Prmt1 | Btg1 | ENSRNOP00000063624 | ENSRNOP00000005910 | Protein arginine N-methyltransferase 1; Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, ILF3, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15, EWS, HABP4 and SERBP1. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation (By similarity). Methylates H4R3 in genes involved in glioblastomagenesis in a CHTOP- and/or TET1 [...] | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | 0.638 |
Rnmt | Btg1 | ENSRNOP00000022410 | ENSRNOP00000005910 | mRNA cap guanine-N7 methyltransferase; Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'- terminal GpppC; Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family. | Protein BTG1; Anti-proliferative protein; Belongs to the BTG family. | 0.474 |