STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Emc2ER membrane protein complex subunit 2; Belongs to the EMC2 family. (296 aa)    
Predicted Functional Partners:
Emc4
ER membrane protein complex subunit 4; Belongs to the EMC4 family.
   
 0.999
Emc3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
   
 0.999
Emc6
ER membrane protein complex subunit 6.
   
 0.999
Emc1
Similar to KIAA0090 protein (Predicted), isoform CRA_a.
   
 0.999
Emc8
ER membrane protein complex subunit 8; Belongs to the EMC8/EMC9 family.
   
 0.996
Mmgt1
Membrane magnesium transporter 1; Mediates Mg(2+) transport.
   
 0.995
Emc9
ER membrane protein complex subunit 9; Belongs to the EMC8/EMC9 family.
   
 0.994
Emc10
ER membrane protein complex subunit 10; Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways.
    
 0.992
Emc7
ER membrane protein complex subunit 7.
   
 0.990
Dctn4
Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
    
 
 0.865
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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