node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dazl | Dppa3 | ENSRNOP00000070802 | ENSRNOP00000036033 | Deleted in azoospermia-like. | Developmental pluripotency-associated protein 3; Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) o [...] | 0.718 |
Dazl | Nanos3 | ENSRNOP00000070802 | ENSRNOP00000045882 | Deleted in azoospermia-like. | Nanos homolog 3 (Drosophila) (Predicted); Belongs to the nanos family. | 0.821 |
Dazl | Prdm14 | ENSRNOP00000070802 | ENSRNOP00000032955 | Deleted in azoospermia-like. | PR/SET domain 14. | 0.825 |
Dazl | Tfap2c | ENSRNOP00000070802 | ENSRNOP00000006991 | Deleted in azoospermia-like. | Transcription factor AP-2, gamma. | 0.691 |
Dppa3 | Dazl | ENSRNOP00000036033 | ENSRNOP00000070802 | Developmental pluripotency-associated protein 3; Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) o [...] | Deleted in azoospermia-like. | 0.718 |
Dppa3 | Nanos3 | ENSRNOP00000036033 | ENSRNOP00000045882 | Developmental pluripotency-associated protein 3; Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) o [...] | Nanos homolog 3 (Drosophila) (Predicted); Belongs to the nanos family. | 0.636 |
Dppa3 | Prdm14 | ENSRNOP00000036033 | ENSRNOP00000032955 | Developmental pluripotency-associated protein 3; Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) o [...] | PR/SET domain 14. | 0.736 |
Dppa3 | Tfap2c | ENSRNOP00000036033 | ENSRNOP00000006991 | Developmental pluripotency-associated protein 3; Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) o [...] | Transcription factor AP-2, gamma. | 0.619 |
Elf5 | Foxa1 | ENSRNOP00000011035 | ENSRNOP00000009940 | E74-like ETS transcription factor 5. | Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. Proposed to play a role in translating the epigenetic signatures into cell type- [...] | 0.497 |
Elf5 | Gata3 | ENSRNOP00000011035 | ENSRNOP00000026187 | E74-like ETS transcription factor 5. | GATA-binding protein 3. | 0.737 |
Elf5 | Tfap2c | ENSRNOP00000011035 | ENSRNOP00000006991 | E74-like ETS transcription factor 5. | Transcription factor AP-2, gamma. | 0.630 |
Foxa1 | Elf5 | ENSRNOP00000009940 | ENSRNOP00000011035 | Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. Proposed to play a role in translating the epigenetic signatures into cell type- [...] | E74-like ETS transcription factor 5. | 0.497 |
Foxa1 | Gata3 | ENSRNOP00000009940 | ENSRNOP00000026187 | Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. Proposed to play a role in translating the epigenetic signatures into cell type- [...] | GATA-binding protein 3. | 0.989 |
Foxa1 | Tfap2c | ENSRNOP00000009940 | ENSRNOP00000006991 | Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. Proposed to play a role in translating the epigenetic signatures into cell type- [...] | Transcription factor AP-2, gamma. | 0.661 |
Gata3 | Elf5 | ENSRNOP00000026187 | ENSRNOP00000011035 | GATA-binding protein 3. | E74-like ETS transcription factor 5. | 0.737 |
Gata3 | Foxa1 | ENSRNOP00000026187 | ENSRNOP00000009940 | GATA-binding protein 3. | Hepatocyte nuclear factor 3-alpha; Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'- [AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. Proposed to play a role in translating the epigenetic signatures into cell type- [...] | 0.989 |
Gata3 | Myc | ENSRNOP00000026187 | ENSRNOP00000006188 | GATA-binding protein 3. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (By similarity). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | 0.475 |
Gata3 | Tfap2c | ENSRNOP00000026187 | ENSRNOP00000006991 | GATA-binding protein 3. | Transcription factor AP-2, gamma. | 0.762 |
Kctd1 | Tfap2c | ENSRNOP00000058222 | ENSRNOP00000006991 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | Transcription factor AP-2, gamma. | 0.738 |
Kdm5b | Myc | ENSRNOP00000073808 | ENSRNOP00000006188 | Lysine demethylase 5B. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (By similarity). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | 0.850 |