node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cnot1 | Cnot4 | ENSRNOP00000016563 | ENSRNOP00000046140 | CCR4-NOT transcription complex, subunit 1. | CCR4-NOT transcription complex, subunit 4. | 0.988 |
Cnot1 | Cnot9 | ENSRNOP00000016563 | ENSRNOP00000021548 | CCR4-NOT transcription complex, subunit 1. | CCR4-NOT transcription complex subunit 9; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down- regulation of MYB- and JUN-dependent transcription. Enhances ligand- dependent transcriptional activity of nuclear hormone receptors. May play a role in cell d [...] | 0.999 |
Cnot1 | Rida | ENSRNOP00000016563 | ENSRNOP00000007430 | CCR4-NOT transcription complex, subunit 1. | 2-iminobutanoate/2-iminopropanoate deaminase; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'- phosphate-dependent dehydratases including L-threonine dehydratase. | 0.753 |
Cnot1 | Ythdf2 | ENSRNOP00000016563 | ENSRNOP00000014479 | CCR4-NOT transcription complex, subunit 1. | YTH N(6)-methyladenosine RNA-binding protein 2. | 0.735 |
Cnot4 | Cnot1 | ENSRNOP00000046140 | ENSRNOP00000016563 | CCR4-NOT transcription complex, subunit 4. | CCR4-NOT transcription complex, subunit 1. | 0.988 |
Cnot4 | Cnot9 | ENSRNOP00000046140 | ENSRNOP00000021548 | CCR4-NOT transcription complex, subunit 4. | CCR4-NOT transcription complex subunit 9; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down- regulation of MYB- and JUN-dependent transcription. Enhances ligand- dependent transcriptional activity of nuclear hormone receptors. May play a role in cell d [...] | 0.996 |
Cnot4 | Exosc7 | ENSRNOP00000046140 | ENSRNOP00000069523 | CCR4-NOT transcription complex, subunit 4. | Exosome component 7. | 0.936 |
Cnot4 | Rida | ENSRNOP00000046140 | ENSRNOP00000007430 | CCR4-NOT transcription complex, subunit 4. | 2-iminobutanoate/2-iminopropanoate deaminase; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'- phosphate-dependent dehydratases including L-threonine dehydratase. | 0.788 |
Cnot9 | Cnot1 | ENSRNOP00000021548 | ENSRNOP00000016563 | CCR4-NOT transcription complex subunit 9; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down- regulation of MYB- and JUN-dependent transcription. Enhances ligand- dependent transcriptional activity of nuclear hormone receptors. May play a role in cell d [...] | CCR4-NOT transcription complex, subunit 1. | 0.999 |
Cnot9 | Cnot4 | ENSRNOP00000021548 | ENSRNOP00000046140 | CCR4-NOT transcription complex subunit 9; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down- regulation of MYB- and JUN-dependent transcription. Enhances ligand- dependent transcriptional activity of nuclear hormone receptors. May play a role in cell d [...] | CCR4-NOT transcription complex, subunit 4. | 0.996 |
Cnot9 | Rida | ENSRNOP00000021548 | ENSRNOP00000007430 | CCR4-NOT transcription complex subunit 9; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down- regulation of MYB- and JUN-dependent transcription. Enhances ligand- dependent transcriptional activity of nuclear hormone receptors. May play a role in cell d [...] | 2-iminobutanoate/2-iminopropanoate deaminase; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'- phosphate-dependent dehydratases including L-threonine dehydratase. | 0.789 |
Exosc7 | Cnot4 | ENSRNOP00000069523 | ENSRNOP00000046140 | Exosome component 7. | CCR4-NOT transcription complex, subunit 4. | 0.936 |
Exosc7 | Rida | ENSRNOP00000069523 | ENSRNOP00000007430 | Exosome component 7. | 2-iminobutanoate/2-iminopropanoate deaminase; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'- phosphate-dependent dehydratases including L-threonine dehydratase. | 0.702 |
Hacl1 | Rida | ENSRNOP00000026588 | ENSRNOP00000007430 | 2-hydroxyacyl-CoA lyase 1; Catalyzes a carbon-carbon cleavage reaction; cleaves a 2- hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde; Belongs to the TPP enzyme family. | 2-iminobutanoate/2-iminopropanoate deaminase; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'- phosphate-dependent dehydratases including L-threonine dehydratase. | 0.676 |
Hacl1 | Sds | ENSRNOP00000026588 | ENSRNOP00000001876 | 2-hydroxyacyl-CoA lyase 1; Catalyzes a carbon-carbon cleavage reaction; cleaves a 2- hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde; Belongs to the TPP enzyme family. | L-serine dehydratase/L-threonine deaminase; Belongs to the serine/threonine dehydratase family. | 0.737 |
Hacl1 | Sdsl | ENSRNOP00000026588 | ENSRNOP00000001882 | 2-hydroxyacyl-CoA lyase 1; Catalyzes a carbon-carbon cleavage reaction; cleaves a 2- hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde; Belongs to the TPP enzyme family. | Serine dehydratase-like (Predicted). | 0.638 |
Hacl1 | Srr | ENSRNOP00000026588 | ENSRNOP00000050774 | 2-hydroxyacyl-CoA lyase 1; Catalyzes a carbon-carbon cleavage reaction; cleaves a 2- hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde; Belongs to the TPP enzyme family. | Serine racemase; Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. | 0.628 |
Hacl1 | Ugcg | ENSRNOP00000026588 | ENSRNOP00000021110 | 2-hydroxyacyl-CoA lyase 1; Catalyzes a carbon-carbon cleavage reaction; cleaves a 2- hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde; Belongs to the TPP enzyme family. | Ceramide glucosyltransferase; Catalyzes at the cytosolic surface of the Golgi, the initial step of the glucosylceramide-based glycosphingolipid/GSL synthetic pathway, the transfer of glucose from UDP-glucose to ceramide to produce glucosylceramide/GlcCer. Glucosylceramide is the core component of glycosphingolipids/GSLs, amphipathic molecules consisting of a ceramide lipid moiety embedded in the outer leaflet of the membrane, linked to one of hundreds of different externally oriented oligosaccharide structures. Glycosphingolipids are essential components of membrane microdomains that m [...] | 0.628 |
Rida | Cnot1 | ENSRNOP00000007430 | ENSRNOP00000016563 | 2-iminobutanoate/2-iminopropanoate deaminase; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'- phosphate-dependent dehydratases including L-threonine dehydratase. | CCR4-NOT transcription complex, subunit 1. | 0.753 |
Rida | Cnot4 | ENSRNOP00000007430 | ENSRNOP00000046140 | 2-iminobutanoate/2-iminopropanoate deaminase; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'- phosphate-dependent dehydratases including L-threonine dehydratase. | CCR4-NOT transcription complex, subunit 4. | 0.788 |