Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Acbd5-2 | Fis1 | ENSRNOP00000072836 | ENSRNOP00000061895 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | 0.679 |
| Acbd5-2 | Gdap1 | ENSRNOP00000072836 | ENSRNOP00000007994 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | 0.699 |
| Acbd5-2 | LOC100911356 | ENSRNOP00000072836 | ENSRNOP00000032453 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. | 0.773 |
| Acbd5-2 | Pex26 | ENSRNOP00000072836 | ENSRNOP00000065481 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Similar to peroxisome biogenesis factor 26. | 0.683 |
| Acbd5-2 | Pxmp4 | ENSRNOP00000072836 | ENSRNOP00000022914 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Peroxisomal membrane protein 4. | 0.737 |
| Fis1 | Acbd5-2 | ENSRNOP00000061895 | ENSRNOP00000072836 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | 0.679 |
| Fis1 | Gdap1 | ENSRNOP00000061895 | ENSRNOP00000007994 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | 0.870 |
| Fis1 | LOC100911356 | ENSRNOP00000061895 | ENSRNOP00000032453 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. | 0.829 |
| Fis1 | LOC100911485 | ENSRNOP00000061895 | ENSRNOP00000059463 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Mitofusin-2; Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (By similarity). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Plays an important role in the regulation [...] | 0.983 |
| Fis1 | Mfn2 | ENSRNOP00000061895 | ENSRNOP00000070746 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Mitofusin 2. | 0.984 |
| Fis1 | Pex26 | ENSRNOP00000061895 | ENSRNOP00000065481 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Similar to peroxisome biogenesis factor 26. | 0.745 |
| Fis1 | Pxmp4 | ENSRNOP00000061895 | ENSRNOP00000022914 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Peroxisomal membrane protein 4. | 0.571 |
| Gdap1 | Acbd5-2 | ENSRNOP00000007994 | ENSRNOP00000072836 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | 0.699 |
| Gdap1 | Fis1 | ENSRNOP00000007994 | ENSRNOP00000061895 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | 0.870 |
| Gdap1 | LOC100911356 | ENSRNOP00000007994 | ENSRNOP00000032453 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Peroxisomal biogenesis factor 19; Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. | 0.720 |
| Gdap1 | LOC100911485 | ENSRNOP00000007994 | ENSRNOP00000059463 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Mitofusin-2; Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (By similarity). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Plays an important role in the regulation [...] | 0.756 |
| Gdap1 | Mfn2 | ENSRNOP00000007994 | ENSRNOP00000070746 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Mitofusin 2. | 0.756 |
| Gdap1 | Pex26 | ENSRNOP00000007994 | ENSRNOP00000065481 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Similar to peroxisome biogenesis factor 26. | 0.710 |
| Gdap1 | Pxmp4 | ENSRNOP00000007994 | ENSRNOP00000022914 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | Peroxisomal membrane protein 4. | 0.680 |
| Gdap1 | Sbf2 | ENSRNOP00000007994 | ENSRNOP00000013126 | Ganglioside-induced differentiation-associated-protein 1 (Predicted); Belongs to the GST superfamily. | SET-binding factor 2. | 0.706 |
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