STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Trim54Tripartite motif-containing protein 54; May bind and stabilize microtubules during myotubes formation. (364 aa)    
Predicted Functional Partners:
Nrap
Nebulin-related-anchoring protein.
   
 
 0.723
Ttn
Uncharacterized protein.
   
 
 0.711
Ckmt2
Creatine kinase S-type, mitochondrial; Belongs to the ATP:guanido phosphotransferase family.
   
 
 0.678
Actn2
Actinin alpha 2.
   
 
 0.656
Fbxo32
F-box only protein 32; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity).
   
  
 0.646
Tcap
Uncharacterized protein.
   
 
 0.646
Nbr1
Next to BRCA1 gene 1 protein; Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.
    
 
 0.575
Ccdc152
Coiled-coil domain-containing 152.
      
 0.571
Trim34
Tripartite motif-containing 34.
    
 
 0.570
Myoz1
Myozenin 1.
   
 
 0.558
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.