STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pum2Pumilio RNA-binding family member 2. (1061 aa)    
Predicted Functional Partners:
Pum1
Pumilio RNA-binding family member 1.
  
0.944
Nanos1
Nanos C2HC-type zinc finger 1; Belongs to the nanos family.
   
 
 0.932
Atxn1
Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved brain development.
   
 
 0.923
Atxn1l
Alanine and glycine-rich protein-like.
     
 0.900
Dazl
Deleted in azoospermia-like.
    
 
 0.772
Nanos3
Nanos homolog 3 (Drosophila) (Predicted); Belongs to the nanos family.
   
 
 0.766
Cnot1
CCR4-NOT transcription complex, subunit 1.
   
 
 0.761
Cnot7
CCR4-NOT transcription complex, subunit 7.
   
 
 0.743
Cox17
Cytochrome C oxidase assembly protein COX17.
   
 
 0.702
Cnot8
CCR4-NOT transcription complex, subunit 8, isoform CRA_a.
   
 
 0.694
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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