STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Necab1N-terminal EF-hand calcium-binding protein 1. (352 aa)    
Predicted Functional Partners:
Wdr90
WD repeat domain 90.
   
 
 0.749
Efr3a
Similar to RIKEN cDNA C920006C10 (Predicted).
   
  
 0.606
Soga3
SOGA family member 3.
   
  
 0.597
Ctxn1
Cortexin-1; May mediate extracellular or intracellular signaling of cortical neurons during forebrain development.
   
  
 0.577
Mien1
Similar to RIKEN cDNA 1810046J19 (Predicted).
   
 
 0.564
Necab2
N-terminal EF-hand calcium-binding protein 2; May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation.
   
 
0.555
Klhl32
Kelch-like family member 32.
   
  
 0.555
Pcdhgb5
Protocadherin gamma subfamily B, 5.
    
 
 0.543
Agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3.
   
  
 0.540
LOC103689978
SUMO-specific peptidase 5.
    
 
 0.532
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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