STRINGSTRING
Fntb protein (Rattus norvegicus) - STRING interaction network
"Fntb" - Protein farnesyltransferase subunit beta in Rattus norvegicus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FntbProtein farnesyltransferase subunit beta ; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C- terminus of several proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X (437 aa)    
Predicted Functional Partners:
Fnta
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha ; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation (377 aa)
     
  0.999
Ggps1
Geranylgeranyl pyrophosphate synthase ; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins (300 aa)
     
  0.977
Rce1
CAAX prenyl protease 2 (329 aa)
     
  0.967
Zmpste24
CAAX prenyl protease 1 homolog (475 aa)
     
 
  0.966
Rabggta
Geranylgeranyl transferase type-2 subunit alpha ; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A (567 aa)
     
  0.959
Pdss1
Prenyl (solanesyl) diphosphate synthase, subunit 1 (409 aa)
     
  0.958
Pdss2
Decaprenyl-diphosphate synthase subunit 2 ; Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10 (401 aa)
     
  0.957
Dhdds
Dehydrodolichyl diphosphate synthase ; Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (333 aa)
     
 
  0.942
Nus1
Nuclear undecaprenyl pyrophosphate synthase 1 (293 aa)
     
 
  0.911
Gngt1
Guanine nucleotide-binding protein G(T) subunit gamma-T1 ; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (74 aa)
       
    0.902
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
Server load: low (3%) [HD]