node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Allc | Dpys | ENSRNOP00000011048 | ENSRNOP00000006004 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | Dihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. | 0.510 |
Allc | Dpysl2 | ENSRNOP00000011048 | ENSRNOP00000012996 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | Dihydropyrimidinase-related protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | 0.510 |
Allc | Dpysl5 | ENSRNOP00000011048 | ENSRNOP00000012274 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | Dihydropyrimidinase-related protein 5; May have a function in neuronal differentiation and/or axon growth; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | 0.510 |
Allc | Efcab10 | ENSRNOP00000011048 | ENSRNOP00000014252 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | EF-hand calcium-binding domain 10. | 0.570 |
Allc | Fos | ENSRNOP00000011048 | ENSRNOP00000010712 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling (By similarity). Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] | 0.697 |
Allc | Gtf3c5 | ENSRNOP00000011048 | ENSRNOP00000015068 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | General transcription factor IIIC, polypeptide 5. | 0.665 |
Allc | Myc | ENSRNOP00000011048 | ENSRNOP00000006188 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (By similarity). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). | 0.512 |
Allc | Nt5c1b | ENSRNOP00000011048 | ENSRNOP00000070166 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | 5'-nucleotidase, cytosolic IB. | 0.550 |
Allc | RGD1309350 | ENSRNOP00000011048 | ENSRNOP00000067773 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | 5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.549 |
Allc | Uox | ENSRNOP00000011048 | ENSRNOP00000021970 | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. | 0.751 |
Dpys | Allc | ENSRNOP00000006004 | ENSRNOP00000011048 | Dihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | 0.510 |
Dpys | Dpysl2 | ENSRNOP00000006004 | ENSRNOP00000012996 | Dihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. | Dihydropyrimidinase-related protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | 0.534 |
Dpys | Dpysl5 | ENSRNOP00000006004 | ENSRNOP00000012274 | Dihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. | Dihydropyrimidinase-related protein 5; May have a function in neuronal differentiation and/or axon growth; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | 0.508 |
Dpys | Uox | ENSRNOP00000006004 | ENSRNOP00000021970 | Dihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. | 0.452 |
Dpysl2 | Allc | ENSRNOP00000012996 | ENSRNOP00000011048 | Dihydropyrimidinase-related protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | 0.510 |
Dpysl2 | Dpys | ENSRNOP00000012996 | ENSRNOP00000006004 | Dihydropyrimidinase-related protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | Dihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. | 0.534 |
Dpysl2 | Dpysl5 | ENSRNOP00000012996 | ENSRNOP00000012274 | Dihydropyrimidinase-related protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | Dihydropyrimidinase-related protein 5; May have a function in neuronal differentiation and/or axon growth; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | 0.967 |
Dpysl5 | Allc | ENSRNOP00000012274 | ENSRNOP00000011048 | Dihydropyrimidinase-related protein 5; May have a function in neuronal differentiation and/or axon growth; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | Probable allantoicase; The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals. | 0.510 |
Dpysl5 | Dpys | ENSRNOP00000012274 | ENSRNOP00000006004 | Dihydropyrimidinase-related protein 5; May have a function in neuronal differentiation and/or axon growth; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | Dihydropyrimidinase; Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. | 0.508 |
Dpysl5 | Dpysl2 | ENSRNOP00000012274 | ENSRNOP00000012996 | Dihydropyrimidinase-related protein 5; May have a function in neuronal differentiation and/or axon growth; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | Dihydropyrimidinase-related protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. | 0.967 |