node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amot | Crb3 | ENSRNOP00000070184 | ENSRNOP00000070535 | Angiomotin. | Crumbs homolog 3 (Drosophila), isoform CRA_b. | 0.664 |
Amot | Mpdz | ENSRNOP00000070184 | ENSRNOP00000072433 | Angiomotin. | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. | 0.972 |
Amot | Mpp5 | ENSRNOP00000070184 | ENSRNOP00000012005 | Angiomotin. | MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface (By similarity). Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (By similarity). Required during embryonic and postnatal retinal development (By similarity). Required [...] | 0.994 |
Amot | Patj | ENSRNOP00000070184 | ENSRNOP00000010211 | Angiomotin. | InaD-like protein; Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions (By similarity). May regulate the surface expression and/or function of ASIC3 in sensory neurons (By similarity). May recruit ARHGEF18 to apical cell-cell boundaries (By similarity). | 0.999 |
Crb1 | Crb3 | ENSRNOP00000037018 | ENSRNOP00000070535 | Crumbs homolog 1 (Drosophila) (Predicted). | Crumbs homolog 3 (Drosophila), isoform CRA_b. | 0.896 |
Crb1 | Mpdz | ENSRNOP00000037018 | ENSRNOP00000072433 | Crumbs homolog 1 (Drosophila) (Predicted). | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. | 0.812 |
Crb1 | Mpp5 | ENSRNOP00000037018 | ENSRNOP00000012005 | Crumbs homolog 1 (Drosophila) (Predicted). | MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface (By similarity). Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (By similarity). Required during embryonic and postnatal retinal development (By similarity). Required [...] | 0.942 |
Crb1 | Patj | ENSRNOP00000037018 | ENSRNOP00000010211 | Crumbs homolog 1 (Drosophila) (Predicted). | InaD-like protein; Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions (By similarity). May regulate the surface expression and/or function of ASIC3 in sensory neurons (By similarity). May recruit ARHGEF18 to apical cell-cell boundaries (By similarity). | 0.976 |
Crb3 | Amot | ENSRNOP00000070535 | ENSRNOP00000070184 | Crumbs homolog 3 (Drosophila), isoform CRA_b. | Angiomotin. | 0.664 |
Crb3 | Crb1 | ENSRNOP00000070535 | ENSRNOP00000037018 | Crumbs homolog 3 (Drosophila), isoform CRA_b. | Crumbs homolog 1 (Drosophila) (Predicted). | 0.896 |
Crb3 | Mpdz | ENSRNOP00000070535 | ENSRNOP00000072433 | Crumbs homolog 3 (Drosophila), isoform CRA_b. | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. | 0.792 |
Crb3 | Mpp5 | ENSRNOP00000070535 | ENSRNOP00000012005 | Crumbs homolog 3 (Drosophila), isoform CRA_b. | MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface (By similarity). Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (By similarity). Required during embryonic and postnatal retinal development (By similarity). Required [...] | 0.919 |
Crb3 | Pard6a | ENSRNOP00000070535 | ENSRNOP00000069044 | Crumbs homolog 3 (Drosophila), isoform CRA_b. | Partitioning defective 6 homolog alpha; Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization. Belongs to the PAR6 family. | 0.408 |
Crb3 | Pard6b | ENSRNOP00000070535 | ENSRNOP00000014568 | Crumbs homolog 3 (Drosophila), isoform CRA_b. | Par-6 (Partitioning defective 6) homolog beta (C. elegans) (Predicted). | 0.500 |
Crb3 | Patj | ENSRNOP00000070535 | ENSRNOP00000010211 | Crumbs homolog 3 (Drosophila), isoform CRA_b. | InaD-like protein; Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions (By similarity). May regulate the surface expression and/or function of ASIC3 in sensory neurons (By similarity). May recruit ARHGEF18 to apical cell-cell boundaries (By similarity). | 0.984 |
Mpdz | Amot | ENSRNOP00000072433 | ENSRNOP00000070184 | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. | Angiomotin. | 0.972 |
Mpdz | Crb1 | ENSRNOP00000072433 | ENSRNOP00000037018 | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. | Crumbs homolog 1 (Drosophila) (Predicted). | 0.812 |
Mpdz | Crb3 | ENSRNOP00000072433 | ENSRNOP00000070535 | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. | Crumbs homolog 3 (Drosophila), isoform CRA_b. | 0.792 |
Mpdz | Mpp5 | ENSRNOP00000072433 | ENSRNOP00000012005 | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. | MAGUK p55 subfamily member 5; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface (By similarity). Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (By similarity). Required during embryonic and postnatal retinal development (By similarity). Required [...] | 0.989 |
Mpdz | Patj | ENSRNOP00000072433 | ENSRNOP00000010211 | Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. | InaD-like protein; Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions (By similarity). May regulate the surface expression and/or function of ASIC3 in sensory neurons (By similarity). May recruit ARHGEF18 to apical cell-cell boundaries (By similarity). | 0.844 |