node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dnajc15 | Grpel1 | ENSRNOP00000012530 | ENSRNOP00000070967 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | 0.885 |
Dnajc15 | Hspa9 | ENSRNOP00000012530 | ENSRNOP00000026696 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging. | 0.873 |
Dnajc15 | LOC100910944 | ENSRNOP00000012530 | ENSRNOP00000064235 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | Reactive oxygen species modulator 1-like. | 0.766 |
Dnajc15 | LOC100911130 | ENSRNOP00000012530 | ENSRNOP00000038100 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. | 0.786 |
Dnajc15 | Pam16 | ENSRNOP00000012530 | ENSRNOP00000006314 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | Mitochondrial import inner membrane translocase subunit TIM16; Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity (By similarity); Belongs to the TIM16/PAM16 family. | 0.978 |
Dnajc15 | Timm17a | ENSRNOP00000012530 | ENSRNOP00000009398 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | Mitochondrial import inner membrane translocase subunit Tim17-A; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. | 0.869 |
Dnajc15 | Timm17b | ENSRNOP00000012530 | ENSRNOP00000059538 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | Mitochondrial import inner membrane translocase subunit Tim17-B-like. | 0.786 |
Dnajc15 | Timm21 | ENSRNOP00000012530 | ENSRNOP00000020376 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | Mitochondrial import inner membrane translocase subunit Tim21; Participates in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes. | 0.856 |
Dnajc15 | Timm23 | ENSRNOP00000012530 | ENSRNOP00000026932 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | Mitochondrial import inner membrane translocase subunit Tim23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. | 0.889 |
Dnajc15 | Timm44 | ENSRNOP00000012530 | ENSRNOP00000001409 | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source. | 0.852 |
Grpel1 | Dnajc15 | ENSRNOP00000070967 | ENSRNOP00000012530 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | DnaJ (Hsp40) homolog, subfamily C, member 15 (Predicted), isoform CRA_a. | 0.885 |
Grpel1 | Hspa9 | ENSRNOP00000070967 | ENSRNOP00000026696 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging. | 0.976 |
Grpel1 | LOC100910944 | ENSRNOP00000070967 | ENSRNOP00000064235 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | Reactive oxygen species modulator 1-like. | 0.769 |
Grpel1 | LOC100911130 | ENSRNOP00000070967 | ENSRNOP00000038100 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. | 0.735 |
Grpel1 | Pam16 | ENSRNOP00000070967 | ENSRNOP00000006314 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | Mitochondrial import inner membrane translocase subunit TIM16; Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity (By similarity); Belongs to the TIM16/PAM16 family. | 0.939 |
Grpel1 | Timm17a | ENSRNOP00000070967 | ENSRNOP00000009398 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | Mitochondrial import inner membrane translocase subunit Tim17-A; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. | 0.847 |
Grpel1 | Timm17b | ENSRNOP00000070967 | ENSRNOP00000059538 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | Mitochondrial import inner membrane translocase subunit Tim17-B-like. | 0.735 |
Grpel1 | Timm21 | ENSRNOP00000070967 | ENSRNOP00000020376 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | Mitochondrial import inner membrane translocase subunit Tim21; Participates in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes. | 0.818 |
Grpel1 | Timm23 | ENSRNOP00000070967 | ENSRNOP00000026932 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | Mitochondrial import inner membrane translocase subunit Tim23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. | 0.829 |
Grpel1 | Timm44 | ENSRNOP00000070967 | ENSRNOP00000001409 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins; Belongs to the GrpE family. | Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source. | 0.945 |