STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Scrn1Secernin-1; Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity). (414 aa)    
Predicted Functional Partners:
Vapa
Vesicle-associated membrane protein-associated protein A; Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites (By similarity). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (By similarity). With OSBPL3, may regulate ER morphology (By similarity). May play a role in vesicle trafficking.
    
 
 0.708
Magea11
Melanoma antigen family A, 11.
    
 
 0.473
Fsd1
Similar to fibronectin type 3 and SPRY domain-containing protein, isoform CRA_a.
    
 
 0.465
Prrc1
Protein PRRC1.
      
 0.439
Muc19
Uncharacterized protein.
      
 0.438
LOC100360573
40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.
    
 
 0.417
D4AAJ3_RAT
40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.
    
 
 0.417
D3ZG05_RAT
40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.
    
 
 0.417
D4A9C8_RAT
40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.
    
 
 0.417
D3ZEB8_RAT
40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.
    
 
 0.417
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.