STRINGSTRING
RGD1564420 protein (Rattus norvegicus) - STRING interaction network
"RGD1564420" - Similar to Hypothetical protein MGC31278 in Rattus norvegicus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RGD1564420Similar to Hypothetical protein MGC31278 (1159 aa)    
Predicted Functional Partners:
RGD1309995
Similar to CG13957-PA (1173 aa)
     
 
  0.973
Ccdc53
RCG48807, isoform CRA_a; Coiled-coil domain containing 53 (194 aa)
     
 
  0.953
Fam21c
WASH complex subunit 2; Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes inhibits WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization and is involved in the fission of tubules that serve as transport intermediates during endosome sorting. Mediates the recruitment of the WASH core complex to endosome membranes via binding to phospholipids and VPS35 of the retromer CSC. Mediates the recruitment of the F-actin-capping protein dimer to the WASH core complex proba [...] (1328 aa)
     
 
  0.947
Wash
WASH complex subunit 1; Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Its assembly in the WASH core complex seems to inhibit its NPF activity and via WASHC2 is required for its membrane targeting. Regulates the trafficking of endosomal alpha5beta1 integrin to the plasma membrane and involved in invasive cell migration. In T-cells involved in endosome-to-membrane recycling of re [...] (427 aa)
       
 
  0.905
Ppp2r4
Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (323 aa)
 
            0.691
Ccdc43
Coiled-coil domain containing 43; Belongs to the CCDC43 family (222 aa)
     
   
  0.678
Spast
Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails- severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (524 aa)
     
   
  0.676
Spg11
SPG11, spatacsin vesicle-trafficking-associated; Spastic paraplegia 11 (autosomal recessive) (2315 aa)
     
   
  0.673
Vps37a
Similar to DNA segment, Chr 8, ERATO Doi 531, expressed, isoform CRA_c; Vacuolar protein sorting 37 homolog A (S. cerevisiae) (398 aa)
     
   
  0.667
Heatr5b
HEAT repeat containing 5B (2030 aa)
     
   
  0.632
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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