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Acot2 protein (Rattus norvegicus) - STRING interaction network
"Acot2" - Acyl-coenzyme A thioesterase 2, mitochondrial in Rattus norvegicus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Acot2Acyl-coenzyme A thioesterase 2, mitochondrial ; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Most active on substrates with chain lengths ranging from C14-C20 (453 aa)    
Predicted Functional Partners:
Acot1
Acyl-coenzyme A thioesterase 1 ; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (417 aa)
   
 
0.937
Tecr
Trans-2,3-enoyl-CoA reductase ; Catalyzes the last of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lip [...] (308 aa)
     
 
  0.906
Pfkp
6-phosphofructokinase type C ; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (786 aa)
   
 
  0.816
Pfkm
6-phosphofructokinase, muscle type ; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (780 aa)
   
 
  0.816
Acot4
Acyl-coenzyme A thioesterase 4 (421 aa)
   
 
0.815
Pfkl
6-phosphofructokinase, liver type ; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (780 aa)
   
 
    0.814
Acot3
acyl-CoA thioesterase 3 (430 aa)
   
 
0.806
Fbp2
Fructose-1,6-bisphosphatase isozyme 2 ; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate (339 aa)
         
  0.803
Acot5
Acyl-coenzyme A thioesterase 5 (421 aa)
   
   
0.802
Fbp1
Fructose bisphosphatase 1 (367 aa)
         
    0.800
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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