Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Akt1 | Hspb2 | ENSRNOP00000038369 | ENSRNOP00000013960 | RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...] | Heat shock protein beta-2; May regulate the kinase DMPK. | 0.807 |
| Akt1 | Hspb3 | ENSRNOP00000038369 | ENSRNOP00000014627 | RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...] | Heat shock protein beta-3; Inhibitor of actin polymerization; Belongs to the small heat shock protein (HSP20) family. | 0.523 |
| Akt1 | Mapk11 | ENSRNOP00000038369 | ENSRNOP00000009325 | RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...] | Mitogen-activated protein kinase. | 0.943 |
| Akt1 | Mapk12 | ENSRNOP00000038369 | ENSRNOP00000046455 | RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...] | Mitogen-activated protein kinase 12; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstre [...] | 0.938 |
| Akt1 | Mapk13 | ENSRNOP00000038369 | ENSRNOP00000000621 | RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...] | Mitogen-activated protein kinase 13; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studie [...] | 0.939 |
| Akt1 | Mapk14 | ENSRNOP00000038369 | ENSRNOP00000000617 | RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...] | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | 0.968 |
| Cryab | Hspb2 | ENSRNOP00000055901 | ENSRNOP00000013960 | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein beta-2; May regulate the kinase DMPK. | 0.810 |
| Cryab | Hspb8 | ENSRNOP00000055901 | ENSRNOP00000033432 | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein beta-8; Displays temperature-dependent chaperone activity. | 0.716 |
| Cryab | Hspb9 | ENSRNOP00000055901 | ENSRNOP00000052123 | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein, alpha-crystallin-related, B9 (Predicted); Belongs to the small heat shock protein (HSP20) family. | 0.572 |
| Hspb2 | Akt1 | ENSRNOP00000013960 | ENSRNOP00000038369 | Heat shock protein beta-2; May regulate the kinase DMPK. | RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...] | 0.807 |
| Hspb2 | Cryab | ENSRNOP00000013960 | ENSRNOP00000055901 | Heat shock protein beta-2; May regulate the kinase DMPK. | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions; Belongs to the small heat shock protein (HSP20) family. | 0.810 |
| Hspb2 | Hspb3 | ENSRNOP00000013960 | ENSRNOP00000014627 | Heat shock protein beta-2; May regulate the kinase DMPK. | Heat shock protein beta-3; Inhibitor of actin polymerization; Belongs to the small heat shock protein (HSP20) family. | 0.927 |
| Hspb2 | Hspb7 | ENSRNOP00000013960 | ENSRNOP00000042240 | Heat shock protein beta-2; May regulate the kinase DMPK. | Heat shock protein beta-7. | 0.899 |
| Hspb2 | Hspb8 | ENSRNOP00000013960 | ENSRNOP00000033432 | Heat shock protein beta-2; May regulate the kinase DMPK. | Heat shock protein beta-8; Displays temperature-dependent chaperone activity. | 0.766 |
| Hspb2 | Hspb9 | ENSRNOP00000013960 | ENSRNOP00000052123 | Heat shock protein beta-2; May regulate the kinase DMPK. | Heat shock protein, alpha-crystallin-related, B9 (Predicted); Belongs to the small heat shock protein (HSP20) family. | 0.830 |
| Hspb2 | Mapk11 | ENSRNOP00000013960 | ENSRNOP00000009325 | Heat shock protein beta-2; May regulate the kinase DMPK. | Mitogen-activated protein kinase. | 0.950 |
| Hspb2 | Mapk12 | ENSRNOP00000013960 | ENSRNOP00000046455 | Heat shock protein beta-2; May regulate the kinase DMPK. | Mitogen-activated protein kinase 12; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstre [...] | 0.948 |
| Hspb2 | Mapk13 | ENSRNOP00000013960 | ENSRNOP00000000621 | Heat shock protein beta-2; May regulate the kinase DMPK. | Mitogen-activated protein kinase 13; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studie [...] | 0.924 |
| Hspb2 | Mapk14 | ENSRNOP00000013960 | ENSRNOP00000000617 | Heat shock protein beta-2; May regulate the kinase DMPK. | Mitogen-activated protein kinase 14; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are a [...] | 0.960 |
| Hspb3 | Akt1 | ENSRNOP00000014627 | ENSRNOP00000038369 | Heat shock protein beta-3; Inhibitor of actin polymerization; Belongs to the small heat shock protein (HSP20) family. | RAC-alpha serine/threonine-protein kinase; AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the [...] | 0.523 |
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