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Slc7a7 protein (Rattus norvegicus) - STRING interaction network
"Slc7a7" - Y+L amino acid transporter 1 in Rattus norvegicus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Slc7a7Y+L amino acid transporter 1 ; Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis via transport of L-arginine, and is involved in the transport of L-arginine in monocytes (By similarity) (512 aa)    
Predicted Functional Partners:
Bsg
Basigin ; Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes (388 aa)
     
 
  0.901
Cad
CAD protein (2224 aa)
     
   
  0.635
Acacb
acetyl-CoA carboxylase 2 (2460 aa)
   
   
  0.591
Acaca
acetyl-CoA carboxylase 1 ; Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (2030 aa)
   
   
  0.591
Slc3a2
4F2 cell-surface antigen heavy chain ; Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umb [...] (527 aa)
     
 
  0.585
Acly
ATP-citrate synthase isoform 1 ; ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine (1101 aa)
     
   
  0.575
Slc3a1
Neutral and basic amino acid transport protein rBAT ; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule (683 aa)
     
 
  0.571
Slc1a4
Neutral amino acid transporter A (529 aa)
   
   
  0.537
Slc1a7
Excitatory amino acid transporter 5 (570 aa)
   
   
  0.534
Gart
Trifunctional purine biosynthetic protein adenosine-3 (1010 aa)
   
   
  0.510
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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