node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Agl | Gaa | ENSRNOP00000052593 | ENSRNOP00000064500 | Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. | Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. | 0.552 |
Agl | Gbe1 | ENSRNOP00000052593 | ENSRNOP00000068640 | Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. | Glucan (1,4-alpha-), branching enzyme 1. | 0.991 |
Agl | Gyg1 | ENSRNOP00000052593 | ENSRNOP00000070350 | Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | 0.958 |
Agl | Gys1 | ENSRNOP00000052593 | ENSRNOP00000028271 | Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. | Glycogen [starch] synthase, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family. | 0.911 |
Agl | Gys2 | ENSRNOP00000052593 | ENSRNOP00000074743 | Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. | Glycogen [starch] synthase, liver; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family. | 0.886 |
Agl | Ppp1r3c | ENSRNOP00000052593 | ENSRNOP00000024941 | Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. | Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types (By similarity). | 0.660 |
Gaa | Agl | ENSRNOP00000064500 | ENSRNOP00000052593 | Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. | Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. | 0.552 |
Gaa | Gyg1 | ENSRNOP00000064500 | ENSRNOP00000070350 | Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | 0.823 |
Gbe1 | Agl | ENSRNOP00000068640 | ENSRNOP00000052593 | Glucan (1,4-alpha-), branching enzyme 1. | Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. | 0.991 |
Gbe1 | Gyg1 | ENSRNOP00000068640 | ENSRNOP00000070350 | Glucan (1,4-alpha-), branching enzyme 1. | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | 0.975 |
Gbe1 | Gys1 | ENSRNOP00000068640 | ENSRNOP00000028271 | Glucan (1,4-alpha-), branching enzyme 1. | Glycogen [starch] synthase, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family. | 0.998 |
Gbe1 | Gys2 | ENSRNOP00000068640 | ENSRNOP00000074743 | Glucan (1,4-alpha-), branching enzyme 1. | Glycogen [starch] synthase, liver; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family. | 0.996 |
Gbe1 | Ppp1r3c | ENSRNOP00000068640 | ENSRNOP00000024941 | Glucan (1,4-alpha-), branching enzyme 1. | Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types (By similarity). | 0.536 |
Gyg1 | Agl | ENSRNOP00000070350 | ENSRNOP00000052593 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. | 0.958 |
Gyg1 | Gaa | ENSRNOP00000070350 | ENSRNOP00000064500 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | Lysosomal alpha-glucosidase; Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. | 0.823 |
Gyg1 | Gbe1 | ENSRNOP00000070350 | ENSRNOP00000068640 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | Glucan (1,4-alpha-), branching enzyme 1. | 0.975 |
Gyg1 | Gys1 | ENSRNOP00000070350 | ENSRNOP00000028271 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | Glycogen [starch] synthase, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family. | 0.995 |
Gyg1 | Gys2 | ENSRNOP00000070350 | ENSRNOP00000074743 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | Glycogen [starch] synthase, liver; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Belongs to the glycosyltransferase 3 family. | 0.911 |
Gyg1 | Pold1 | ENSRNOP00000070350 | ENSRNOP00000026797 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol- delta4), displays differences in catalytic activity. Most notably, expresses higher pro [...] | 0.700 |
Gyg1 | Pold2 | ENSRNOP00000070350 | ENSRNOP00000072093 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. | DNA polymerase delta subunit 2; Accessory component of both the DNA polymerase delta complex and the DNA polymerase zeta complex. As a component of the trimeric and tetrameric DNA polymerase delta complexes (Pol-delta3 and Pol-delta4, respectively), plays a role in high fidelity genome replication, including in lagging strand synthesis, and repair. Pol-delta3 and Pol- delta4 are characterized by the absence or the presence of POLD4. They exhibit differences in catalytic activity. Most notably, Pol-delta3 shows higher proofreading activity than Pol-delta4. Although both Pol- delta3 and [...] | 0.708 |