node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ak2 | Dusp26 | ENSRNOP00000000134 | ENSRNOP00000015725 | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.568 |
Def8 | Dusp26 | ENSRNOP00000000281 | ENSRNOP00000015725 | Differentially expressed in FDCP 8 homolog; Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption. Belongs to the DEF8 family. | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.515 |
Dusp26 | Ak2 | ENSRNOP00000015725 | ENSRNOP00000000134 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. | 0.568 |
Dusp26 | Def8 | ENSRNOP00000015725 | ENSRNOP00000000281 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Differentially expressed in FDCP 8 homolog; Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption. Belongs to the DEF8 family. | 0.515 |
Dusp26 | Eps8l2 | ENSRNOP00000015725 | ENSRNOP00000024725 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Eps8l2 protein. | 0.472 |
Dusp26 | Hdhd5 | ENSRNOP00000015725 | ENSRNOP00000015090 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Cat eye syndrome chromosome region, candidate 5 homolog (Human) (Predicted). | 0.677 |
Dusp26 | Hipk2 | ENSRNOP00000015725 | ENSRNOP00000060564 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Homeodomain interacting protein kinase 2 (Predicted), isoform CRA_a. | 0.661 |
Dusp26 | Lipt2 | ENSRNOP00000015725 | ENSRNOP00000022879 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. | 0.510 |
Dusp26 | Mettl17 | ENSRNOP00000015725 | ENSRNOP00000062157 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Methyltransferase-like 17. | 0.523 |
Dusp26 | Smim12 | ENSRNOP00000015725 | ENSRNOP00000019224 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Small integral membrane protein 12. | 0.430 |
Dusp26 | Vsir | ENSRNOP00000015725 | ENSRNOP00000054563 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | V-set immunoregulatory receptor. | 0.499 |
Dusp26 | Ypel2 | ENSRNOP00000015725 | ENSRNOP00000007379 | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Yippee-like 2. | 0.505 |
Eps8l2 | Dusp26 | ENSRNOP00000024725 | ENSRNOP00000015725 | Eps8l2 protein. | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.472 |
Hdhd5 | Dusp26 | ENSRNOP00000015090 | ENSRNOP00000015725 | Cat eye syndrome chromosome region, candidate 5 homolog (Human) (Predicted). | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.677 |
Hdhd5 | Mettl17 | ENSRNOP00000015090 | ENSRNOP00000062157 | Cat eye syndrome chromosome region, candidate 5 homolog (Human) (Predicted). | Methyltransferase-like 17. | 0.471 |
Hipk2 | Dusp26 | ENSRNOP00000060564 | ENSRNOP00000015725 | Homeodomain interacting protein kinase 2 (Predicted), isoform CRA_a. | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.661 |
Lipt2 | Dusp26 | ENSRNOP00000022879 | ENSRNOP00000015725 | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.510 |
Lipt2 | Mettl17 | ENSRNOP00000022879 | ENSRNOP00000062157 | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. | Methyltransferase-like 17. | 0.723 |
Mettl17 | Dusp26 | ENSRNOP00000062157 | ENSRNOP00000015725 | Methyltransferase-like 17. | Dual specificity protein phosphatase 26; Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.523 |
Mettl17 | Hdhd5 | ENSRNOP00000062157 | ENSRNOP00000015090 | Methyltransferase-like 17. | Cat eye syndrome chromosome region, candidate 5 homolog (Human) (Predicted). | 0.471 |