STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Olig3Oligodendrocyte transcription factor 3. (273 aa)    
Predicted Functional Partners:
Dbx1
Homeobox protein DBX1; Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity).
   
  
 0.655
Gbx2
Gastrulation brain homeobox 2.
   
  
 0.652
Tlx3
Similar to HOX11L2 (Predicted), isoform CRA_a.
      
 0.552
Dbx2
Developing brain homeobox 2.
      
 0.547
Lmx1b
LIM homeobox transcription factor 1 beta.
      
 0.543
Tcf24
Transcription factor 24.
   
 
 0.506
Phox2b
Paired-like homeobox 2b.
   
  
 0.469
Tnfaip3
TNF alpha-induced protein 3.
      
 0.467
Baiap2l2
BAI1-associated protein 2-like 2.
   
  
 0.462
Tcf12
Transcription factor 12; Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3') (By similarity).
    
 
 0.462
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
Server load: medium (54%) [HD]