STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZfrZinc finger RNA-binding protein; Involved in postimplantation and gastrulation stages of development (By similarity). Binds to DNA and RNA (By similarity). Involved in the nucleocytoplasmic shuttling of STAU2. (1074 aa)    
Predicted Functional Partners:
Ilf2
Interleukin enhancer-binding factor 2; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA (By similarity). Essential for the efficient reshuttling of ILF3 into the nucleus (By similarity).
   
 
0.688
Nanos2
Nanos C2HC-type zinc finger 2; Belongs to the nanos family.
      
 0.516
Abt1
Activator of basal transcription 1; May be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity).
   
  
 0.500
Ubap2
Ubiquitin-associated protein 2.
   
 
 0.494
Armc7
Armadillo repeat-containing 7.
      
 0.451
Rsl1d1
Ac1158.
   
 
 0.450
Mtmr12
Myotubularin-related protein 12; Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis. Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.
   
  
 0.445
Gfra1
GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor; Belongs to the GDNFR family.
      
 0.444
Rsl1d1l1
Ribosomal L1 domain-containing protein 1-like.
    
 
 0.444
Zranb2
Zinc finger Ran-binding domain-containing protein 2; Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection (By similarity).
   
 
 0.441
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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