node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Commd6 | Tedc2 | ENSRNOP00000054640 | ENSRNOP00000046320 | Similar to OTTHUMP00000018508 (Predicted), isoform CRA_a. | Tubulin epsilon and delta complex 2. | 0.660 |
Commd6 | Znf740 | ENSRNOP00000054640 | ENSRNOP00000016240 | Similar to OTTHUMP00000018508 (Predicted), isoform CRA_a. | Zinc finger protein 740. | 0.535 |
Dedd | Znf740 | ENSRNOP00000005147 | ENSRNOP00000016240 | Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity). | Zinc finger protein 740. | 0.439 |
Ipo13 | Tedc2 | ENSRNOP00000026844 | ENSRNOP00000046320 | Importin-13; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis re [...] | Tubulin epsilon and delta complex 2. | 0.653 |
Ipo13 | Znf740 | ENSRNOP00000026844 | ENSRNOP00000016240 | Importin-13; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis re [...] | Zinc finger protein 740. | 0.496 |
Med13l | Znf740 | ENSRNOP00000070275 | ENSRNOP00000016240 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Zinc finger protein 740. | 0.510 |
Mprip | Znf740 | ENSRNOP00000069198 | ENSRNOP00000016240 | Myosin phosphatase Rho-interacting protein; Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin- binding region leads to disassembly of stress fibers in neuronal cells (By similarity). | Zinc finger protein 740. | 0.421 |
Tcfl5 | Znf740 | ENSRNOP00000070754 | ENSRNOP00000016240 | Transcription factor-like 5. | Zinc finger protein 740. | 0.532 |
Tedc2 | Commd6 | ENSRNOP00000046320 | ENSRNOP00000054640 | Tubulin epsilon and delta complex 2. | Similar to OTTHUMP00000018508 (Predicted), isoform CRA_a. | 0.660 |
Tedc2 | Ipo13 | ENSRNOP00000046320 | ENSRNOP00000026844 | Tubulin epsilon and delta complex 2. | Importin-13; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis re [...] | 0.653 |
Tedc2 | Znf740 | ENSRNOP00000046320 | ENSRNOP00000016240 | Tubulin epsilon and delta complex 2. | Zinc finger protein 740. | 0.512 |
Trim28 | Znf740 | ENSRNOP00000031061 | ENSRNOP00000016240 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 740. | 0.543 |
Znf740 | Commd6 | ENSRNOP00000016240 | ENSRNOP00000054640 | Zinc finger protein 740. | Similar to OTTHUMP00000018508 (Predicted), isoform CRA_a. | 0.535 |
Znf740 | Dedd | ENSRNOP00000016240 | ENSRNOP00000005147 | Zinc finger protein 740. | Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity). | 0.439 |
Znf740 | Ipo13 | ENSRNOP00000016240 | ENSRNOP00000026844 | Zinc finger protein 740. | Importin-13; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis re [...] | 0.496 |
Znf740 | Med13l | ENSRNOP00000016240 | ENSRNOP00000070275 | Zinc finger protein 740. | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.510 |
Znf740 | Mprip | ENSRNOP00000016240 | ENSRNOP00000069198 | Zinc finger protein 740. | Myosin phosphatase Rho-interacting protein; Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin- binding region leads to disassembly of stress fibers in neuronal cells (By similarity). | 0.421 |
Znf740 | Tcfl5 | ENSRNOP00000016240 | ENSRNOP00000070754 | Zinc finger protein 740. | Transcription factor-like 5. | 0.532 |
Znf740 | Tedc2 | ENSRNOP00000016240 | ENSRNOP00000046320 | Zinc finger protein 740. | Tubulin epsilon and delta complex 2. | 0.512 |
Znf740 | Trim28 | ENSRNOP00000016240 | ENSRNOP00000031061 | Zinc finger protein 740. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.543 |