node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bcap31 | Fis1 | ENSRNOP00000070305 | ENSRNOP00000061895 | B-cell receptor-associated protein 31, isoform CRA_a. | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | 0.996 |
Bcap31 | Hspa9 | ENSRNOP00000070305 | ENSRNOP00000026696 | B-cell receptor-associated protein 31, isoform CRA_a. | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging. | 0.685 |
Bcap31 | LOC100911485 | ENSRNOP00000070305 | ENSRNOP00000059463 | B-cell receptor-associated protein 31, isoform CRA_a. | Mitofusin-2; Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (By similarity). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Plays an important role in the regulation [...] | 0.718 |
Bcap31 | LOC686087 | ENSRNOP00000070305 | ENSRNOP00000073210 | B-cell receptor-associated protein 31, isoform CRA_a. | Similar to motile sperm domain containing 1. | 0.590 |
Bcap31 | Mfn2 | ENSRNOP00000070305 | ENSRNOP00000070746 | B-cell receptor-associated protein 31, isoform CRA_a. | Mitofusin 2. | 0.718 |
Bcap31 | Mospd1 | ENSRNOP00000070305 | ENSRNOP00000003192 | B-cell receptor-associated protein 31, isoform CRA_a. | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to- mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | 0.590 |
Bcap31 | Mospd2 | ENSRNOP00000070305 | ENSRNOP00000074561 | B-cell receptor-associated protein 31, isoform CRA_a. | Motile sperm domain-containing 2. | 0.430 |
Bcap31 | Pacs2 | ENSRNOP00000070305 | ENSRNOP00000053720 | B-cell receptor-associated protein 31, isoform CRA_a. | Phosphofurin acidic cluster sorting protein 2. | 0.951 |
Bcap31 | Rmdn3 | ENSRNOP00000070305 | ENSRNOP00000016356 | B-cell receptor-associated protein 31, isoform CRA_a. | Regulator of microtubule dynamics protein 3; Involved in cellular calcium homeostasis regulation (By similarity). May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis (By similarity). Belongs to the RMDN family. | 0.682 |
Bcap31 | Vapb | ENSRNOP00000070305 | ENSRNOP00000007554 | B-cell receptor-associated protein 31, isoform CRA_a. | Vesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation; Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. | 0.937 |
Fis1 | Bcap31 | ENSRNOP00000061895 | ENSRNOP00000070305 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | B-cell receptor-associated protein 31, isoform CRA_a. | 0.996 |
Fis1 | Hspa9 | ENSRNOP00000061895 | ENSRNOP00000026696 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging. | 0.643 |
Fis1 | LOC100911485 | ENSRNOP00000061895 | ENSRNOP00000059463 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Mitofusin-2; Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (By similarity). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Plays an important role in the regulation [...] | 0.983 |
Fis1 | Mfn2 | ENSRNOP00000061895 | ENSRNOP00000070746 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Mitofusin 2. | 0.984 |
Fis1 | Mospd2 | ENSRNOP00000061895 | ENSRNOP00000074561 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Motile sperm domain-containing 2. | 0.446 |
Fis1 | Pacs2 | ENSRNOP00000061895 | ENSRNOP00000053720 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Phosphofurin acidic cluster sorting protein 2. | 0.613 |
Fis1 | Rmdn3 | ENSRNOP00000061895 | ENSRNOP00000016356 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Regulator of microtubule dynamics protein 3; Involved in cellular calcium homeostasis regulation (By similarity). May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis (By similarity). Belongs to the RMDN family. | 0.580 |
Fis1 | Vapb | ENSRNOP00000061895 | ENSRNOP00000007554 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | Vesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation; Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. | 0.790 |
Hspa9 | Bcap31 | ENSRNOP00000026696 | ENSRNOP00000070305 | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging. | B-cell receptor-associated protein 31, isoform CRA_a. | 0.685 |
Hspa9 | Fis1 | ENSRNOP00000026696 | ENSRNOP00000061895 | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging. | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (By similarity); Belongs to the FIS1 family. | 0.643 |