node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NMS | Npb | ENSRNOP00000056345 | ENSRNOP00000051836 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. Stimulates the contraction of rectum and elevation of blood pressure; Belongs to the NmU family. | Neuropeptide B-29; May be involved in the regulation of feeding, neuroendocrine system, memory and learning. May be involved in the afferent pain pathway (By similarity). | 0.663 |
NMS | Npw | ENSRNOP00000056345 | ENSRNOP00000016554 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. Stimulates the contraction of rectum and elevation of blood pressure; Belongs to the NmU family. | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress. When injected into the lateral cerebroventricle, it elevates prolactin (PRL) and corticosterone and lowers growth hormone (GH) release; Belongs to the neuropeptide B/W family. | 0.555 |
NMS | Oxt | ENSRNOP00000056345 | ENSRNOP00000028829 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. Stimulates the contraction of rectum and elevation of blood pressure; Belongs to the NmU family. | Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin. | 0.414 |
NMS | Pmch | ENSRNOP00000056345 | ENSRNOP00000006174 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. Stimulates the contraction of rectum and elevation of blood pressure; Belongs to the NmU family. | Neuropeptide-glutamic acid-isoleucine; MCH inhibits ACTH secretion at the end of the light on period which corresponds to the peak of the circadian rhythm in ACTH. Inhibits also stress induced ACTH release during the light off period of the cycle. Involved as a neurotransmitter or neuromodulator in a broad array of neuronal functions. Stimulates sexual behavior when injected into the ventromedial nucleus, this effect is antagonized by NEI. In the medial preoptic area, stimulates anxiety and sexual behavior. Antagonizes inhibitory effect of melanotropin alpha on exploration behavior. | 0.414 |
NMS | Rln3 | ENSRNOP00000056345 | ENSRNOP00000007775 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. Stimulates the contraction of rectum and elevation of blood pressure; Belongs to the NmU family. | Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity); Belongs to the insulin family. | 0.467 |
NMS | Tor2a | ENSRNOP00000056345 | ENSRNOP00000030747 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. Stimulates the contraction of rectum and elevation of blood pressure; Belongs to the NmU family. | Torsin-2A. | 0.575 |
Npb | NMS | ENSRNOP00000051836 | ENSRNOP00000056345 | Neuropeptide B-29; May be involved in the regulation of feeding, neuroendocrine system, memory and learning. May be involved in the afferent pain pathway (By similarity). | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. Stimulates the contraction of rectum and elevation of blood pressure; Belongs to the NmU family. | 0.663 |
Npb | Npbwr1 | ENSRNOP00000051836 | ENSRNOP00000010032 | Neuropeptide B-29; May be involved in the regulation of feeding, neuroendocrine system, memory and learning. May be involved in the afferent pain pathway (By similarity). | Neuropeptides B/W receptor type 1; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.999 |
Npb | Npw | ENSRNOP00000051836 | ENSRNOP00000016554 | Neuropeptide B-29; May be involved in the regulation of feeding, neuroendocrine system, memory and learning. May be involved in the afferent pain pathway (By similarity). | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress. When injected into the lateral cerebroventricle, it elevates prolactin (PRL) and corticosterone and lowers growth hormone (GH) release; Belongs to the neuropeptide B/W family. | 0.994 |
Npb | Oxt | ENSRNOP00000051836 | ENSRNOP00000028829 | Neuropeptide B-29; May be involved in the regulation of feeding, neuroendocrine system, memory and learning. May be involved in the afferent pain pathway (By similarity). | Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin. | 0.537 |
Npb | Rln3 | ENSRNOP00000051836 | ENSRNOP00000007775 | Neuropeptide B-29; May be involved in the regulation of feeding, neuroendocrine system, memory and learning. May be involved in the afferent pain pathway (By similarity). | Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity); Belongs to the insulin family. | 0.544 |
Npb | Trh | ENSRNOP00000051836 | ENSRNOP00000015944 | Neuropeptide B-29; May be involved in the regulation of feeding, neuroendocrine system, memory and learning. May be involved in the afferent pain pathway (By similarity). | Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems; Belongs to the TRH family. | 0.443 |
Npbwr1 | Npb | ENSRNOP00000010032 | ENSRNOP00000051836 | Neuropeptides B/W receptor type 1; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Neuropeptide B-29; May be involved in the regulation of feeding, neuroendocrine system, memory and learning. May be involved in the afferent pain pathway (By similarity). | 0.999 |
Npbwr1 | Npw | ENSRNOP00000010032 | ENSRNOP00000016554 | Neuropeptides B/W receptor type 1; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress. When injected into the lateral cerebroventricle, it elevates prolactin (PRL) and corticosterone and lowers growth hormone (GH) release; Belongs to the neuropeptide B/W family. | 0.999 |
Npw | NMS | ENSRNOP00000016554 | ENSRNOP00000056345 | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress. When injected into the lateral cerebroventricle, it elevates prolactin (PRL) and corticosterone and lowers growth hormone (GH) release; Belongs to the neuropeptide B/W family. | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. Stimulates the contraction of rectum and elevation of blood pressure; Belongs to the NmU family. | 0.555 |
Npw | Npb | ENSRNOP00000016554 | ENSRNOP00000051836 | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress. When injected into the lateral cerebroventricle, it elevates prolactin (PRL) and corticosterone and lowers growth hormone (GH) release; Belongs to the neuropeptide B/W family. | Neuropeptide B-29; May be involved in the regulation of feeding, neuroendocrine system, memory and learning. May be involved in the afferent pain pathway (By similarity). | 0.994 |
Npw | Npbwr1 | ENSRNOP00000016554 | ENSRNOP00000010032 | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress. When injected into the lateral cerebroventricle, it elevates prolactin (PRL) and corticosterone and lowers growth hormone (GH) release; Belongs to the neuropeptide B/W family. | Neuropeptides B/W receptor type 1; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.999 |
Npw | Oxt | ENSRNOP00000016554 | ENSRNOP00000028829 | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress. When injected into the lateral cerebroventricle, it elevates prolactin (PRL) and corticosterone and lowers growth hormone (GH) release; Belongs to the neuropeptide B/W family. | Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin. | 0.631 |
Npw | Pmch | ENSRNOP00000016554 | ENSRNOP00000006174 | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress. When injected into the lateral cerebroventricle, it elevates prolactin (PRL) and corticosterone and lowers growth hormone (GH) release; Belongs to the neuropeptide B/W family. | Neuropeptide-glutamic acid-isoleucine; MCH inhibits ACTH secretion at the end of the light on period which corresponds to the peak of the circadian rhythm in ACTH. Inhibits also stress induced ACTH release during the light off period of the cycle. Involved as a neurotransmitter or neuromodulator in a broad array of neuronal functions. Stimulates sexual behavior when injected into the ventromedial nucleus, this effect is antagonized by NEI. In the medial preoptic area, stimulates anxiety and sexual behavior. Antagonizes inhibitory effect of melanotropin alpha on exploration behavior. | 0.476 |
Npw | Rln3 | ENSRNOP00000016554 | ENSRNOP00000007775 | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress. When injected into the lateral cerebroventricle, it elevates prolactin (PRL) and corticosterone and lowers growth hormone (GH) release; Belongs to the neuropeptide B/W family. | Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity); Belongs to the insulin family. | 0.533 |