node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gsta1 | Gstk1 | ENSRNOP00000018325 | ENSRNOP00000022275 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | 0.849 |
Gsta1 | Gstm1 | ENSRNOP00000018325 | ENSRNOP00000039050 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. The olfactory GST may be crucial for the acuity of the olfactory process. | 0.799 |
Gsta1 | Gstm2 | ENSRNOP00000018325 | ENSRNOP00000073172 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione S-transferase Yb-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.942 |
Gsta1 | Gstm3 | ENSRNOP00000018325 | ENSRNOP00000065389 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.740 |
Gsta1 | Gstm3l | ENSRNOP00000018325 | ENSRNOP00000025800 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione S-transferase. | 0.738 |
Gsta1 | Gsto1 | ENSRNOP00000018325 | ENSRNOP00000016851 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.929 |
Gsta1 | Gstp1 | ENSRNOP00000018325 | ENSRNOP00000024601 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity). | 0.745 |
Gsta1 | Gstt1 | ENSRNOP00000018325 | ENSRNOP00000001669 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity. | 0.945 |
Gsta1 | Gstt2 | ENSRNOP00000018325 | ENSRNOP00000071112 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Glutathione S-transferase theta-2; Catalyzes the inactivation of reactive sulfate esters in carcinogenic arylmethanols. Highest activity towards ethacrynic acid and cumene hydroperoxide. | 0.918 |
Gsta1 | Hpgds | ENSRNOP00000018325 | ENSRNOP00000008826 | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | Hematopoietic prostaglandin D synthase; Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. Belongs to the GST superfamily. Sigma family. | 0.747 |
Gstk1 | Gsta1 | ENSRNOP00000022275 | ENSRNOP00000018325 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Glutathione S-transferase alpha-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has substantial activity toward aflatoxin B1-8,9-epoxide. | 0.849 |
Gstk1 | Gstm1 | ENSRNOP00000022275 | ENSRNOP00000039050 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. The olfactory GST may be crucial for the acuity of the olfactory process. | 0.850 |
Gstk1 | Gstm2 | ENSRNOP00000022275 | ENSRNOP00000073172 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Glutathione S-transferase Yb-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.877 |
Gstk1 | Gstm3 | ENSRNOP00000022275 | ENSRNOP00000065389 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.851 |
Gstk1 | Gstm3l | ENSRNOP00000022275 | ENSRNOP00000025800 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Glutathione S-transferase. | 0.855 |
Gstk1 | Gsto1 | ENSRNOP00000022275 | ENSRNOP00000016851 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.893 |
Gstk1 | Gstp1 | ENSRNOP00000022275 | ENSRNOP00000024601 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity). | 0.880 |
Gstk1 | Gstt1 | ENSRNOP00000022275 | ENSRNOP00000001669 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity. | 0.876 |
Gstk1 | Gstt2 | ENSRNOP00000022275 | ENSRNOP00000071112 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Glutathione S-transferase theta-2; Catalyzes the inactivation of reactive sulfate esters in carcinogenic arylmethanols. Highest activity towards ethacrynic acid and cumene hydroperoxide. | 0.882 |
Gstk1 | Hpgds | ENSRNOP00000022275 | ENSRNOP00000008826 | Glutathione S-transferase kappa 1; Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment; Belongs to the GST superfamily. Kappa family. | Hematopoietic prostaglandin D synthase; Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide. Belongs to the GST superfamily. Sigma family. | 0.872 |