STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Zcchc12Zinc finger CCHC domain-containing protein 12; Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic- neuron-specific gene expression (By similarity); Belongs to the ZCCHC12 family. (401 aa)    
Predicted Functional Partners:
Pnma8a
PNMA family member 8A.
  
 
 0.757
Fancm
FA complementation group M.
   
 
 0.726
Rtl6
Retrotransposon Gag-like 6.
   
  
 0.677
rCG_33321
RCG33321, isoform CRA_b.
  
   
 0.628
Rtl9
Retrotransposon Gag-like 9.
    
 
 0.593
Stac2
SH3 and cysteine rich domain 2 (Predicted), isoform CRA_a.
   
 
 0.562
Zik1
Zinc finger protein-interacting with ribonucleoprotein K-like.
    
 0.532
Zik1-2
Zinc finger protein interacting with K protein 1.
    
 0.532
Rtl4
Retrotransposon Gag-like 4.
   
  
 0.491
Rtl3
Retrotransposon Gag-like 3.
    
 
 0.489
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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