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Mvd protein (Rattus norvegicus) - STRING interaction network
"Mvd" - Diphosphomevalonate decarboxylase in Rattus norvegicus
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes; Belongs to the diphosphomevalonate decarboxylase family (401 aa)    
Predicted Functional Partners:
Idi1
Isopentenyl-diphosphate Delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (227 aa)
   
 
  0.998
Pmvk
Phosphomevalonate kinase (194 aa)
     
 
  0.997
Mvk
Mevalonate kinase; May be a regulatory site in cholesterol biosynthetic pathway; Belongs to the GHMP kinase family. Mevalonate kinase subfamily (395 aa)
 
   
  0.995
Fdft1
Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family (416 aa)
   
   
  0.985
Lss
Lanosterol synthase; Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency; Belongs to the terpene cyclase/mutase family (721 aa)
   
 
  0.984
Ggps1
Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins; Belongs to the FPP/GGPP synthase family (300 aa)
   
  0.984
Hmgcs1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase (520 aa)
 
 
  0.975
RGD1564347
Isopentenyl-diphosphate delta isomerase 2-like (227 aa)
   
 
  0.972
Idi2
Similar to isopentenyl diphosphate delta-isomerase type 2 (227 aa)
   
 
  0.972
Cyp51
Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4’-dimethyl cholesta-8,14,24-triene-3-beta-ol; Belongs to the cytochrome P450 family (503 aa)
     
 
  0.960
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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