STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc30a7Zinc transporter 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity). (378 aa)    
Predicted Functional Partners:
Slc39a9
Zinc transporter ZIP9; May act as a zinc-influx transporter; Belongs to the ZIP transporter (TC 2.A.5) family.
   
 
 0.866
Slc39a11
Zinc transporter ZIP11; Functions as a cellular zinc transporter. Belongs to the ZIP transporter (TC 2.A.5) family.
  
 
 0.856
Slc39a13
Zinc transporter ZIP13; Acts as a zinc-influx transporter.
  
 
 0.826
Slc39a8
Zinc transporter ZIP8; Acts as a manganese and zinc influx transporter. Plays a role in manganese reabsorption in the proximal tubule of the kidney and in manganese uptake into the brain; Belongs to the ZIP transporter (TC 2.A.5) family.
  
 
 0.805
Slc39a6
Zinc transporter ZIP6; May act as a zinc-influx transporter.
  
 
 0.805
Slc39a7
Solute carrier family 39 (Zinc transporter), member 7.
  
 
 0.795
Slc30a9
Solute carrier family 30 member 9.
  
 
 0.780
Slc39a14
Solute carrier family 39 (Zinc transporter), member 14 (Predicted).
  
 
 0.697
Slc39a2
Solute carrier family 39 (Zinc transporter), member 2 (Predicted), isoform CRA_a.
   
 
 0.674
Slc39a10
Solute carrier family 39 (Zinc transporter), member 10 (Predicted), isoform CRA_a.
  
 
 0.639
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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