node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dhdds | Fdft1 | ENSRNOP00000020051 | ENSRNOP00000029808 | Alkyl transferase; Belongs to the UPP synthase family. | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. | 0.866 |
Dhdds | Fnta | ENSRNOP00000020051 | ENSRNOP00000019594 | Alkyl transferase; Belongs to the UPP synthase family. | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. | 0.950 |
Dhdds | Fntb | ENSRNOP00000020051 | ENSRNOP00000010588 | Alkyl transferase; Belongs to the UPP synthase family. | Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. | 0.935 |
Dhdds | Ggps1 | ENSRNOP00000020051 | ENSRNOP00000073229 | Alkyl transferase; Belongs to the UPP synthase family. | Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins; Belongs to the FPP/GGPP synthase family. | 0.965 |
Dhdds | Nus1 | ENSRNOP00000020051 | ENSRNOP00000000467 | Alkyl transferase; Belongs to the UPP synthase family. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.991 |
Dhdds | Pdss1 | ENSRNOP00000020051 | ENSRNOP00000065114 | Alkyl transferase; Belongs to the UPP synthase family. | Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. | 0.960 |
Dhdds | Pdss2 | ENSRNOP00000020051 | ENSRNOP00000059060 | Alkyl transferase; Belongs to the UPP synthase family. | Decaprenyl-diphosphate synthase subunit 2; Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10. | 0.957 |
Dhdds | Rce1 | ENSRNOP00000020051 | ENSRNOP00000026454 | Alkyl transferase; Belongs to the UPP synthase family. | CAAX prenyl protease 2; Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K- Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (By similarity). Belongs to the peptidase U48 family. | 0.470 |
Fdft1 | Dhdds | ENSRNOP00000029808 | ENSRNOP00000020051 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. | Alkyl transferase; Belongs to the UPP synthase family. | 0.866 |
Fdft1 | Fnta | ENSRNOP00000029808 | ENSRNOP00000019594 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. | 0.913 |
Fdft1 | Fntb | ENSRNOP00000029808 | ENSRNOP00000010588 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. | Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. | 0.844 |
Fdft1 | Ggps1 | ENSRNOP00000029808 | ENSRNOP00000073229 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. | Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins; Belongs to the FPP/GGPP synthase family. | 0.989 |
Fdft1 | Nus1 | ENSRNOP00000029808 | ENSRNOP00000000467 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.855 |
Fdft1 | Pdss1 | ENSRNOP00000029808 | ENSRNOP00000065114 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. | Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family. | 0.950 |
Fdft1 | Pdss2 | ENSRNOP00000029808 | ENSRNOP00000059060 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. | Decaprenyl-diphosphate synthase subunit 2; Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10. | 0.951 |
Fnta | Dhdds | ENSRNOP00000019594 | ENSRNOP00000020051 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. | Alkyl transferase; Belongs to the UPP synthase family. | 0.950 |
Fnta | Fdft1 | ENSRNOP00000019594 | ENSRNOP00000029808 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway. | 0.913 |
Fnta | Fntb | ENSRNOP00000019594 | ENSRNOP00000010588 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. | Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. | 0.999 |
Fnta | Ggps1 | ENSRNOP00000019594 | ENSRNOP00000073229 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. | Geranylgeranyl pyrophosphate synthase; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins; Belongs to the FPP/GGPP synthase family. | 0.971 |
Fnta | Nus1 | ENSRNOP00000019594 | ENSRNOP00000000467 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.936 |