node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aldh7a1 | Fah | ENSRNOP00000020325 | ENSRNOP00000061132 | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (By similarity). | Fumarylacetoacetase; Belongs to the FAH family. | 0.561 |
Aldh7a1 | Fahd1 | ENSRNOP00000020325 | ENSRNOP00000019767 | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (By similarity). | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | 0.619 |
Aldh7a1 | Fh | ENSRNOP00000020325 | ENSRNOP00000004917 | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (By similarity). | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (By similarity). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [Isoform Cytoplasmic]: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity). Also plays a role in DNA repair by promoting [...] | 0.504 |
Aldh7a1 | Hgd | ENSRNOP00000020325 | ENSRNOP00000003645 | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (By similarity). | Homogentisate 1, 2-dioxygenase. | 0.581 |
Aldh7a1 | Sdha | ENSRNOP00000020325 | ENSRNOP00000018336 | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (By similarity). | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.598 |
Aldh7a1 | Sdhb | ENSRNOP00000020325 | ENSRNOP00000010593 | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (By similarity). | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.531 |
Aldh7a1 | Sdhc | ENSRNOP00000020325 | ENSRNOP00000004228 | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (By similarity). | Succinate dehydrogenase complex, subunit C, integral membrane protein, isoform CRA_b. | 0.437 |
Aldh8a1 | Fah | ENSRNOP00000020015 | ENSRNOP00000061132 | Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. | Fumarylacetoacetase; Belongs to the FAH family. | 0.556 |
Aldh8a1 | Fahd1 | ENSRNOP00000020015 | ENSRNOP00000019767 | Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | 0.546 |
Aldh8a1 | Fh | ENSRNOP00000020015 | ENSRNOP00000004917 | Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (By similarity). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [Isoform Cytoplasmic]: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity). Also plays a role in DNA repair by promoting [...] | 0.491 |
Aldh8a1 | Hgd | ENSRNOP00000020015 | ENSRNOP00000003645 | Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. | Homogentisate 1, 2-dioxygenase. | 0.453 |
Aldh8a1 | Sdha | ENSRNOP00000020015 | ENSRNOP00000018336 | Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.552 |
Aldh8a1 | Sdhb | ENSRNOP00000020015 | ENSRNOP00000010593 | Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.488 |
Aldh8a1 | Sdhc | ENSRNOP00000020015 | ENSRNOP00000004228 | Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. | Succinate dehydrogenase complex, subunit C, integral membrane protein, isoform CRA_b. | 0.417 |
Fah | Aldh7a1 | ENSRNOP00000061132 | ENSRNOP00000020325 | Fumarylacetoacetase; Belongs to the FAH family. | Alpha-aminoadipic semialdehyde dehydrogenase; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (By similarity). | 0.561 |
Fah | Aldh8a1 | ENSRNOP00000061132 | ENSRNOP00000020015 | Fumarylacetoacetase; Belongs to the FAH family. | Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. | 0.556 |
Fah | Fahd1 | ENSRNOP00000061132 | ENSRNOP00000019767 | Fumarylacetoacetase; Belongs to the FAH family. | Acylpyruvase FAHD1, mitochondrial; Probable mitochondrial acylpyruvase which is able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Also has oxaloacetate decarboxylase activity; Belongs to the FAH family. | 0.964 |
Fah | Fh | ENSRNOP00000061132 | ENSRNOP00000004917 | Fumarylacetoacetase; Belongs to the FAH family. | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (By similarity). Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [Isoform Cytoplasmic]: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity). Also plays a role in DNA repair by promoting [...] | 0.880 |
Fah | Hgd | ENSRNOP00000061132 | ENSRNOP00000003645 | Fumarylacetoacetase; Belongs to the FAH family. | Homogentisate 1, 2-dioxygenase. | 0.958 |
Fah | Sdha | ENSRNOP00000061132 | ENSRNOP00000018336 | Fumarylacetoacetase; Belongs to the FAH family. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.857 |