STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TesminTesmin; May have a role in spermatogenesis; Belongs to the lin-54 family. (475 aa)    
Predicted Functional Partners:
Lin52
Lin-52 DREAM MuvB core complex component.
    
 
 0.840
Lin9
Lin-9 DREAM MuvB core complex component.
   
 
 0.781
Naf1
H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4 (By similarity).
   
  
 0.771
Tesl
Testis-derived transcript-like.
   
  
 0.720
Lin37
Similar to RIKEN cDNA 1810054G18 (Predicted), isoform CRA_a.
   
 
 0.667
Zfp318
Zinc finger protein 318.
   
 
 0.662
Wdr73
Neuromedin B (Predicted), isoform CRA_d.
   
 
 0.647
Mybl2
Myeloblastosis oncogene-like 2 (Predicted).
    
 
 0.642
Acr
Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.
      
 0.608
RGD1563620
Similar to retinoblastoma-binding protein 4.
   
 
 0.583
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.