node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dusp18 | Mtmr9 | ENSRNOP00000005516 | ENSRNOP00000015452 | Dual specificity protein phosphatase 18; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). | Myotubularin-related protein 9. | 0.534 |
Dusp18 | Nt5dc2 | ENSRNOP00000005516 | ENSRNOP00000024840 | Dual specificity protein phosphatase 18; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). | 5'-nucleotidase domain-containing protein 2. | 0.521 |
Dusp18 | Plpp6 | ENSRNOP00000005516 | ENSRNOP00000020475 | Dual specificity protein phosphatase 18; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). | Phospholipid phosphatase 6; Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid (By similarity). Belongs to the PA-phosphatase related phosphoesterase family. | 0.536 |
Dusp18 | Ppm1m | ENSRNOP00000005516 | ENSRNOP00000065490 | Dual specificity protein phosphatase 18; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). | Protein phosphatase, Mg2+/Mn2+-dependent, 1M. | 0.548 |
Dusp18 | Pudp | ENSRNOP00000005516 | ENSRNOP00000036211 | Dual specificity protein phosphatase 18; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). | Haloacid dehalogenase-like hydrolase domain containing 1A (Predicted). | 0.603 |
Mtmr9 | Dusp18 | ENSRNOP00000015452 | ENSRNOP00000005516 | Myotubularin-related protein 9. | Dual specificity protein phosphatase 18; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). | 0.534 |
Mtmr9 | Nt5dc2 | ENSRNOP00000015452 | ENSRNOP00000024840 | Myotubularin-related protein 9. | 5'-nucleotidase domain-containing protein 2. | 0.560 |
Mtmr9 | Plpp6 | ENSRNOP00000015452 | ENSRNOP00000020475 | Myotubularin-related protein 9. | Phospholipid phosphatase 6; Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid (By similarity). Belongs to the PA-phosphatase related phosphoesterase family. | 0.670 |
Mtmr9 | Ppm1j | ENSRNOP00000015452 | ENSRNOP00000016833 | Myotubularin-related protein 9. | Protein phosphatase 1J. | 0.509 |
Mtmr9 | Ppm1m | ENSRNOP00000015452 | ENSRNOP00000065490 | Myotubularin-related protein 9. | Protein phosphatase, Mg2+/Mn2+-dependent, 1M. | 0.563 |
Mtmr9 | Pudp | ENSRNOP00000015452 | ENSRNOP00000036211 | Myotubularin-related protein 9. | Haloacid dehalogenase-like hydrolase domain containing 1A (Predicted). | 0.626 |
Nt5dc2 | Dusp18 | ENSRNOP00000024840 | ENSRNOP00000005516 | 5'-nucleotidase domain-containing protein 2. | Dual specificity protein phosphatase 18; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). | 0.521 |
Nt5dc2 | Mtmr9 | ENSRNOP00000024840 | ENSRNOP00000015452 | 5'-nucleotidase domain-containing protein 2. | Myotubularin-related protein 9. | 0.560 |
Nt5dc2 | Plpp6 | ENSRNOP00000024840 | ENSRNOP00000020475 | 5'-nucleotidase domain-containing protein 2. | Phospholipid phosphatase 6; Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid (By similarity). Belongs to the PA-phosphatase related phosphoesterase family. | 0.598 |
Nt5dc2 | Ppm1j | ENSRNOP00000024840 | ENSRNOP00000016833 | 5'-nucleotidase domain-containing protein 2. | Protein phosphatase 1J. | 0.512 |
Nt5dc2 | Ppm1m | ENSRNOP00000024840 | ENSRNOP00000065490 | 5'-nucleotidase domain-containing protein 2. | Protein phosphatase, Mg2+/Mn2+-dependent, 1M. | 0.575 |
Nt5dc2 | Pudp | ENSRNOP00000024840 | ENSRNOP00000036211 | 5'-nucleotidase domain-containing protein 2. | Haloacid dehalogenase-like hydrolase domain containing 1A (Predicted). | 0.628 |
Pigc | Plpp6 | ENSRNOP00000035922 | ENSRNOP00000020475 | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | Phospholipid phosphatase 6; Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid (By similarity). Belongs to the PA-phosphatase related phosphoesterase family. | 0.620 |
Plpp1 | Plpp6 | ENSRNOP00000062843 | ENSRNOP00000020475 | Phospholipid phosphatase 1; Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1- phosphate/C1P. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound (By similarity). Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these b [...] | Phospholipid phosphatase 6; Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid (By similarity). Belongs to the PA-phosphatase related phosphoesterase family. | 0.739 |
Plpp2 | Plpp6 | ENSRNOP00000000193 | ENSRNOP00000020475 | Phospholipid phosphatase 2; Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P. Has no apparent extracellular phosphatase activity and therefore most probably acts intracellularly. Also acts on N-oleoyl ethanolamine phosphate/N- (9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound. Through dephosphorylation of these bioactive lipid mediators produces new bioacti [...] | Phospholipid phosphatase 6; Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid (By similarity). Belongs to the PA-phosphatase related phosphoesterase family. | 0.552 |