node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Guca1a | Guca1b | ENSRNOP00000020902 | ENSRNOP00000020950 | Guanylate cyclase activator 1a (Retina) (Predicted), isoform CRA_a. | Guanylate cyclase activator 1B (Predicted), isoform CRA_a. | 0.936 |
Guca1a | Gucy2d | ENSRNOP00000020902 | ENSRNOP00000020513 | Guanylate cyclase activator 1a (Retina) (Predicted), isoform CRA_a. | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | 0.949 |
Guca1a | Gucy2e | ENSRNOP00000020902 | ENSRNOP00000010790 | Guanylate cyclase activator 1a (Retina) (Predicted), isoform CRA_a. | Retinal guanylyl cyclase 1; Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane. | 0.981 |
Guca1a | Gucy2f | ENSRNOP00000020902 | ENSRNOP00000049500 | Guanylate cyclase activator 1a (Retina) (Predicted), isoform CRA_a. | Retinal guanylyl cyclase 2; Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.956 |
Guca1b | Guca1a | ENSRNOP00000020950 | ENSRNOP00000020902 | Guanylate cyclase activator 1B (Predicted), isoform CRA_a. | Guanylate cyclase activator 1a (Retina) (Predicted), isoform CRA_a. | 0.936 |
Guca1b | Gucy2d | ENSRNOP00000020950 | ENSRNOP00000020513 | Guanylate cyclase activator 1B (Predicted), isoform CRA_a. | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | 0.956 |
Guca1b | Gucy2e | ENSRNOP00000020950 | ENSRNOP00000010790 | Guanylate cyclase activator 1B (Predicted), isoform CRA_a. | Retinal guanylyl cyclase 1; Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane. | 0.966 |
Guca1b | Gucy2f | ENSRNOP00000020950 | ENSRNOP00000049500 | Guanylate cyclase activator 1B (Predicted), isoform CRA_a. | Retinal guanylyl cyclase 2; Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.949 |
Guca1b | Pde6a | ENSRNOP00000020950 | ENSRNOP00000024171 | Guanylate cyclase activator 1B (Predicted), isoform CRA_a. | Phosphodiesterase. | 0.633 |
Guca1b | Pde6b | ENSRNOP00000020950 | ENSRNOP00000000077 | Guanylate cyclase activator 1B (Predicted), isoform CRA_a. | Phosphodiesterase. | 0.603 |
Guca1b | Pde6c | ENSRNOP00000020950 | ENSRNOP00000022317 | Guanylate cyclase activator 1B (Predicted), isoform CRA_a. | Phosphodiesterase. | 0.521 |
Gucy2d | Guca1a | ENSRNOP00000020513 | ENSRNOP00000020902 | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | Guanylate cyclase activator 1a (Retina) (Predicted), isoform CRA_a. | 0.949 |
Gucy2d | Guca1b | ENSRNOP00000020513 | ENSRNOP00000020950 | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | Guanylate cyclase activator 1B (Predicted), isoform CRA_a. | 0.956 |
Gucy2d | Gucy2e | ENSRNOP00000020513 | ENSRNOP00000010790 | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | Retinal guanylyl cyclase 1; Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane. | 0.906 |
Gucy2d | Gucy2f | ENSRNOP00000020513 | ENSRNOP00000049500 | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | Retinal guanylyl cyclase 2; Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity). Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. | 0.914 |
Gucy2d | Itpa | ENSRNOP00000020513 | ENSRNOP00000028838 | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.900 |
Gucy2d | Ncald | ENSRNOP00000020513 | ENSRNOP00000062447 | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | Neurocalcin-delta; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions (By similarity). Belongs to the recoverin family. | 0.966 |
Gucy2d | Pde2a | ENSRNOP00000020513 | ENSRNOP00000026586 | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | cGMP-dependent 3',5'-cyclic phosphodiesterase; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. | 0.866 |
Gucy2d | Pde6a | ENSRNOP00000020513 | ENSRNOP00000024171 | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | Phosphodiesterase. | 0.852 |
Gucy2d | Pde6b | ENSRNOP00000020513 | ENSRNOP00000000077 | Guanylate cyclase 2D; Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (By similarity). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (By similarity). | Phosphodiesterase. | 0.869 |