node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aimp2 | Fubp3 | ENSRNOP00000001379 | ENSRNOP00000021871 | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2- mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. | Far upstream element-binding protein 3. | 0.563 |
Farp2 | Fubp3 | ENSRNOP00000024440 | ENSRNOP00000021871 | FERM, RhoGEF and pleckstrin domain protein 2 (Predicted). | Far upstream element-binding protein 3. | 0.553 |
Fbxo8 | Fubp3 | ENSRNOP00000071387 | ENSRNOP00000021871 | RCG59138, isoform CRA_c. | Far upstream element-binding protein 3. | 0.600 |
Fbxo8 | Lrch1 | ENSRNOP00000071387 | ENSRNOP00000047801 | RCG59138, isoform CRA_c. | Leucine-rich repeats and calponin homology domain-containing 1. | 0.646 |
Fubp3 | Aimp2 | ENSRNOP00000021871 | ENSRNOP00000001379 | Far upstream element-binding protein 3. | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2- mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. | 0.563 |
Fubp3 | Farp2 | ENSRNOP00000021871 | ENSRNOP00000024440 | Far upstream element-binding protein 3. | FERM, RhoGEF and pleckstrin domain protein 2 (Predicted). | 0.553 |
Fubp3 | Fbxo8 | ENSRNOP00000021871 | ENSRNOP00000071387 | Far upstream element-binding protein 3. | RCG59138, isoform CRA_c. | 0.600 |
Fubp3 | Khdc4 | ENSRNOP00000021871 | ENSRNOP00000027385 | Far upstream element-binding protein 3. | KH domain-containing 4, pre-mRNA-splicing factor. | 0.634 |
Fubp3 | Khdrbs1 | ENSRNOP00000021871 | ENSRNOP00000066894 | Far upstream element-binding protein 3. | KH domain-containing, RNA-binding, signal transduction-associated protein 1; Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates [...] | 0.635 |
Fubp3 | Khdrbs2 | ENSRNOP00000021871 | ENSRNOP00000016579 | Far upstream element-binding protein 3. | KH domain-containing, RNA-binding, signal transduction-associated protein 2; RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis (By similarity). Binds both poly(A) and poly(U) homopolymers (By similarity). Phosphorylat [...] | 0.631 |
Fubp3 | Lrch1 | ENSRNOP00000021871 | ENSRNOP00000047801 | Far upstream element-binding protein 3. | Leucine-rich repeats and calponin homology domain-containing 1. | 0.570 |
Fubp3 | Pabpn1l | ENSRNOP00000021871 | ENSRNOP00000050572 | Far upstream element-binding protein 3. | Embryonic polyadenylate-binding protein 2; Binds the poly(A) tail of mRNA. | 0.624 |
Fubp3 | Puf60 | ENSRNOP00000021871 | ENSRNOP00000053317 | Far upstream element-binding protein 3. | Poly(U)-binding-splicing factor PUF60; DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3'-splice si [...] | 0.785 |
Fubp3 | Qk | ENSRNOP00000021871 | ENSRNOP00000070460 | Far upstream element-binding protein 3. | Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). | 0.671 |
Khdc4 | Fubp3 | ENSRNOP00000027385 | ENSRNOP00000021871 | KH domain-containing 4, pre-mRNA-splicing factor. | Far upstream element-binding protein 3. | 0.634 |
Khdrbs1 | Fubp3 | ENSRNOP00000066894 | ENSRNOP00000021871 | KH domain-containing, RNA-binding, signal transduction-associated protein 1; Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates [...] | Far upstream element-binding protein 3. | 0.635 |
Khdrbs1 | Pabpn1l | ENSRNOP00000066894 | ENSRNOP00000050572 | KH domain-containing, RNA-binding, signal transduction-associated protein 1; Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates [...] | Embryonic polyadenylate-binding protein 2; Binds the poly(A) tail of mRNA. | 0.409 |
Khdrbs2 | Fubp3 | ENSRNOP00000016579 | ENSRNOP00000021871 | KH domain-containing, RNA-binding, signal transduction-associated protein 2; RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis (By similarity). Binds both poly(A) and poly(U) homopolymers (By similarity). Phosphorylat [...] | Far upstream element-binding protein 3. | 0.631 |
Khdrbs2 | Pabpn1l | ENSRNOP00000016579 | ENSRNOP00000050572 | KH domain-containing, RNA-binding, signal transduction-associated protein 2; RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis (By similarity). Binds both poly(A) and poly(U) homopolymers (By similarity). Phosphorylat [...] | Embryonic polyadenylate-binding protein 2; Binds the poly(A) tail of mRNA. | 0.552 |
Lrch1 | Fbxo8 | ENSRNOP00000047801 | ENSRNOP00000071387 | Leucine-rich repeats and calponin homology domain-containing 1. | RCG59138, isoform CRA_c. | 0.646 |