node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cdc45 | Cdc6 | ENSRNOP00000066206 | ENSRNOP00000071363 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | 0.977 |
Cdc45 | Cdc7 | ENSRNOP00000066206 | ENSRNOP00000059094 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | Cell division cycle 7 (S. cerevisiae) (Predicted). | 0.953 |
Cdc45 | Gins4 | ENSRNOP00000066206 | ENSRNOP00000024301 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | DNA replication complex GINS protein SLD5, N-terminally processed; The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. SLD5 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA (By similarity). | 0.998 |
Cdc45 | Mcm2 | ENSRNOP00000066206 | ENSRNOP00000022231 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | DNA helicase; Belongs to the MCM family. | 0.999 |
Cdc45 | Mcm3 | ENSRNOP00000066206 | ENSRNOP00000017081 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | DNA helicase; Belongs to the MCM family. | 0.999 |
Cdc45 | Mcm4 | ENSRNOP00000066206 | ENSRNOP00000002510 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | DNA helicase; Belongs to the MCM family. | 0.999 |
Cdc45 | Mcm5 | ENSRNOP00000066206 | ENSRNOP00000070472 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | DNA helicase; Belongs to the MCM family. | 0.999 |
Cdc45 | Mcm6 | ENSRNOP00000066206 | ENSRNOP00000004969 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | DNA replication licensing factor MCM6; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
Cdc45 | Mcm7 | ENSRNOP00000066206 | ENSRNOP00000001825 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
Cdc45 | Orc1 | ENSRNOP00000066206 | ENSRNOP00000012492 | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). | 0.981 |
Cdc6 | Cdc45 | ENSRNOP00000071363 | ENSRNOP00000066206 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | Similar to cell division cycle 45 homolog (S. cerevisiae)-like. | 0.977 |
Cdc6 | Cdc7 | ENSRNOP00000071363 | ENSRNOP00000059094 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | Cell division cycle 7 (S. cerevisiae) (Predicted). | 0.933 |
Cdc6 | Gins4 | ENSRNOP00000071363 | ENSRNOP00000024301 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | DNA replication complex GINS protein SLD5, N-terminally processed; The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. SLD5 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA (By similarity). | 0.764 |
Cdc6 | Mcm2 | ENSRNOP00000071363 | ENSRNOP00000022231 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | DNA helicase; Belongs to the MCM family. | 0.999 |
Cdc6 | Mcm3 | ENSRNOP00000071363 | ENSRNOP00000017081 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | DNA helicase; Belongs to the MCM family. | 0.999 |
Cdc6 | Mcm4 | ENSRNOP00000071363 | ENSRNOP00000002510 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | DNA helicase; Belongs to the MCM family. | 0.999 |
Cdc6 | Mcm5 | ENSRNOP00000071363 | ENSRNOP00000070472 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | DNA helicase; Belongs to the MCM family. | 0.999 |
Cdc6 | Mcm6 | ENSRNOP00000071363 | ENSRNOP00000004969 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | DNA replication licensing factor MCM6; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
Cdc6 | Mcm7 | ENSRNOP00000071363 | ENSRNOP00000001825 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
Cdc6 | Orc1 | ENSRNOP00000071363 | ENSRNOP00000012492 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity). | 0.999 |