node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ace2 | Slc5a2 | ENSRNOP00000047913 | ENSRNOP00000027265 | Processed angiotensin-converting enzyme 2; Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator (By similarity). Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function (By similarity). By cleavage of angiotensin II, may also have a protective role in acute lung injury (By similarity). Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in [...] | Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.443 |
Ace2 | Slc6a18 | ENSRNOP00000047913 | ENSRNOP00000022346 | Processed angiotensin-converting enzyme 2; Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator (By similarity). Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function (By similarity). By cleavage of angiotensin II, may also have a protective role in acute lung injury (By similarity). Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in [...] | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Requires CLTRN for surface expression and for its amino acid transporter activity. | 0.789 |
Cdh16 | Slc12a1 | ENSRNOP00000016419 | ENSRNOP00000073076 | RCG39036, isoform CRA_a. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | 0.401 |
Cdh16 | Slc6a18 | ENSRNOP00000016419 | ENSRNOP00000022346 | RCG39036, isoform CRA_a. | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Requires CLTRN for surface expression and for its amino acid transporter activity. | 0.553 |
Clptm1l | Slc6a18 | ENSRNOP00000023211 | ENSRNOP00000022346 | Similar to cisplatin resistance related protein CRR9p (Predicted). | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Requires CLTRN for surface expression and for its amino acid transporter activity. | 0.633 |
Cltrn | Slc6a18 | ENSRNOP00000005348 | ENSRNOP00000022346 | Collectrin; Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their activity (By similarity). May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane (By similarity). Regulator of SNARE complex function. Stimulator of beta cell replication (By similarity). | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Requires CLTRN for surface expression and for its amino acid transporter activity. | 0.915 |
Slc12a1 | Cdh16 | ENSRNOP00000073076 | ENSRNOP00000016419 | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | RCG39036, isoform CRA_a. | 0.401 |
Slc12a1 | Slc13a1 | ENSRNOP00000073076 | ENSRNOP00000010788 | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | Solute carrier family 13 member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney. | 0.528 |
Slc12a1 | Slc5a2 | ENSRNOP00000073076 | ENSRNOP00000027265 | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.620 |
Slc12a1 | Slc6a18 | ENSRNOP00000073076 | ENSRNOP00000022346 | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Requires CLTRN for surface expression and for its amino acid transporter activity. | 0.557 |
Slc13a1 | Slc12a1 | ENSRNOP00000010788 | ENSRNOP00000073076 | Solute carrier family 13 member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | 0.528 |
Slc13a1 | Slc5a2 | ENSRNOP00000010788 | ENSRNOP00000027265 | Solute carrier family 13 member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney. | Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.578 |
Slc13a1 | Slc6a18 | ENSRNOP00000010788 | ENSRNOP00000022346 | Solute carrier family 13 member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney. | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Requires CLTRN for surface expression and for its amino acid transporter activity. | 0.604 |
Slc36a2 | Slc6a18 | ENSRNOP00000016440 | ENSRNOP00000022346 | Proton-coupled amino acid transporter 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibited by sarcosine. Inhibited by L-pipecolic acid, D-pipecolic acid and isonipecotic acid. Belongs to the amino acid/polyamine transporter 2 family. | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Requires CLTRN for surface expression and for its amino acid transporter activity. | 0.730 |
Slc36a2 | Tmem174 | ENSRNOP00000016440 | ENSRNOP00000020879 | Proton-coupled amino acid transporter 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibited by sarcosine. Inhibited by L-pipecolic acid, D-pipecolic acid and isonipecotic acid. Belongs to the amino acid/polyamine transporter 2 family. | Transmembrane protein 174. | 0.408 |
Slc36a2 | Tmem207 | ENSRNOP00000016440 | ENSRNOP00000066037 | Proton-coupled amino acid transporter 2; Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibited by sarcosine. Inhibited by L-pipecolic acid, D-pipecolic acid and isonipecotic acid. Belongs to the amino acid/polyamine transporter 2 family. | Transmembrane protein 207. | 0.424 |
Slc5a2 | Ace2 | ENSRNOP00000027265 | ENSRNOP00000047913 | Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Processed angiotensin-converting enzyme 2; Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator (By similarity). Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function (By similarity). By cleavage of angiotensin II, may also have a protective role in acute lung injury (By similarity). Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in [...] | 0.443 |
Slc5a2 | Slc12a1 | ENSRNOP00000027265 | ENSRNOP00000073076 | Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | 0.620 |
Slc5a2 | Slc13a1 | ENSRNOP00000027265 | ENSRNOP00000010788 | Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Solute carrier family 13 member 1; Sodium/sulfate cotransporter that mediates sulfate reabsorption in the kidney. | 0.578 |
Slc5a2 | Slc6a18 | ENSRNOP00000027265 | ENSRNOP00000022346 | Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Requires CLTRN for surface expression and for its amino acid transporter activity. | 0.576 |