node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aoc1 | Doxl1 | ENSRNOP00000055909 | ENSRNOP00000033821 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | Amine oxidase. | 0.904 |
Aoc1 | Doxl2 | ENSRNOP00000055909 | ENSRNOP00000048618 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | Amine oxidase; Belongs to the copper/topaquinone oxidase family. | 0.903 |
Aoc1 | Hdc | ENSRNOP00000055909 | ENSRNOP00000041885 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | Histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine. Belongs to the group II decarboxylase family. | 0.967 |
Aoc1 | Hnmt | ENSRNOP00000055909 | ENSRNOP00000007471 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. | 0.982 |
Aoc1 | Hrh1 | ENSRNOP00000055909 | ENSRNOP00000009775 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | Histamine H1 receptor; In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system. | 0.403 |
Aoc1 | Hrh2 | ENSRNOP00000055909 | ENSRNOP00000024580 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | Histamine H2 receptor; The H2 subclass of histamine receptors mediates gastric acid secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | 0.407 |
Aoc1 | Hrh4 | ENSRNOP00000055909 | ENSRNOP00000022744 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | Histamine H4 receptor; The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist) (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.482 |
Doxl1 | Aoc1 | ENSRNOP00000033821 | ENSRNOP00000055909 | Amine oxidase. | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | 0.904 |
Doxl1 | Doxl2 | ENSRNOP00000033821 | ENSRNOP00000048618 | Amine oxidase. | Amine oxidase; Belongs to the copper/topaquinone oxidase family. | 0.907 |
Doxl1 | Hdc | ENSRNOP00000033821 | ENSRNOP00000041885 | Amine oxidase. | Histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine. Belongs to the group II decarboxylase family. | 0.963 |
Doxl1 | Hnmt | ENSRNOP00000033821 | ENSRNOP00000007471 | Amine oxidase. | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. | 0.980 |
Doxl1 | Hrh2 | ENSRNOP00000033821 | ENSRNOP00000024580 | Amine oxidase. | Histamine H2 receptor; The H2 subclass of histamine receptors mediates gastric acid secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | 0.411 |
Doxl1 | Hrh4 | ENSRNOP00000033821 | ENSRNOP00000022744 | Amine oxidase. | Histamine H4 receptor; The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist) (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.560 |
Doxl2 | Aoc1 | ENSRNOP00000048618 | ENSRNOP00000055909 | Amine oxidase; Belongs to the copper/topaquinone oxidase family. | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | 0.903 |
Doxl2 | Doxl1 | ENSRNOP00000048618 | ENSRNOP00000033821 | Amine oxidase; Belongs to the copper/topaquinone oxidase family. | Amine oxidase. | 0.907 |
Doxl2 | Hdc | ENSRNOP00000048618 | ENSRNOP00000041885 | Amine oxidase; Belongs to the copper/topaquinone oxidase family. | Histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine. Belongs to the group II decarboxylase family. | 0.963 |
Doxl2 | Hnmt | ENSRNOP00000048618 | ENSRNOP00000007471 | Amine oxidase; Belongs to the copper/topaquinone oxidase family. | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. | 0.980 |
Doxl2 | Hrh4 | ENSRNOP00000048618 | ENSRNOP00000022744 | Amine oxidase; Belongs to the copper/topaquinone oxidase family. | Histamine H4 receptor; The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist) (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.495 |
Hdc | Aoc1 | ENSRNOP00000041885 | ENSRNOP00000055909 | Histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine. Belongs to the group II decarboxylase family. | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. | 0.967 |
Hdc | Doxl1 | ENSRNOP00000041885 | ENSRNOP00000033821 | Histidine decarboxylase; Catalyzes the biosynthesis of histamine from histidine. Belongs to the group II decarboxylase family. | Amine oxidase. | 0.963 |