STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Abt1Activator of basal transcription 1; May be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity). (268 aa)    
Predicted Functional Partners:
Rrp36
Ribosomal RNA-processing 36.
   
 
 0.991
Ddx10
RNA helicase.
   
 
 0.979
Krr1
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
 
 0.979
Bysl
Bystin; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits.
   
 
 0.978
Ddx49
DEAD-box helicase 49; Belongs to the DEAD box helicase family.
   
 
 0.977
Utp25
Digestive organ expansion factor homolog; Regulates the p53 pathway to control the expansion growth of digestive organs; Belongs to the def family.
   
 
 0.976
Esf1
ESF1 homolog; May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1; Belongs to the ESF1 family.
   
 
 0.975
Nop14
Similar to 2610033H07Rik protein (Predicted), isoform CRA_b.
   
 
 0.974
Utp6
UTP6 small subunit processome component.
   
 
 0.968
Utp18
UTP18 small subunit processome component.
   
 
 0.965
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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