STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Phf23PHD finger protein 23; Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvation or infecting bacteria. Belongs to the PHF23 family. (334 aa)    
Predicted Functional Partners:
Nup98
Nuclear pore complex protein Nup98-Nup96; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. Belongs to the nucleoporin GLFG family.
   
 
 0.738
Mcrs1
Microspherule protein 1.
   
 
 0.648
Lrsam1
Leucine-rich repeat and sterile alpha motif-containing 1.
    
 
 0.583
Tex30
Testis-expressed 30.
   
 
 0.546
Kansl3
KAT8 regulatory NSL complex subunit 3; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
   
 
 0.541
Morc3
MORC family CW-type zinc finger 3.
   
  
 0.540
Nsd1
Nuclear receptor binding SET domain protein 1 (Predicted), isoform CRA_a.
    
 
 0.535
Noc4l
Nucleolar complex protein 4 homolog.
   
  
 0.532
Sin3a
SIN3 transcription regulator family member A.
   
 
 0.529
Cutc
CutC copper transporter homolog (E.coli) (Predicted).
   
  
 0.509
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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