node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acy1 | Acy3 | ENSRNOP00000015852 | ENSRNOP00000024112 | Aminoacylase-1A; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate). | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | 0.796 |
Acy1 | Agmat | ENSRNOP00000015852 | ENSRNOP00000016646 | Aminoacylase-1A; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate). | Agmatinase, mitochondrial; Belongs to the arginase family. Agmatinase subfamily. | 0.401 |
Acy1 | Aspa | ENSRNOP00000015852 | ENSRNOP00000072876 | Aminoacylase-1A; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate). | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | 0.847 |
Acy3 | Acy1 | ENSRNOP00000024112 | ENSRNOP00000015852 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | Aminoacylase-1A; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate). | 0.796 |
Acy3 | Agmat | ENSRNOP00000024112 | ENSRNOP00000016646 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | Agmatinase, mitochondrial; Belongs to the arginase family. Agmatinase subfamily. | 0.475 |
Acy3 | Aspa | ENSRNOP00000024112 | ENSRNOP00000072876 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | 0.613 |
Acy3 | Dhrs9 | ENSRNOP00000024112 | ENSRNOP00000069708 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | Dehydrogenase/reductase SDR family member 9; 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha- tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone (By similarity). Plays also role in the biosynthesis of retinoic acid from retinaldehyde. Can utilize both NADH and NADPH (By similarity). Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.491 |
Acy3 | Noxred1 | ENSRNOP00000024112 | ENSRNOP00000065836 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | NADP-dependent oxidoreductase domain-containing 1. | 0.467 |
Acy3 | Rasal3 | ENSRNOP00000024112 | ENSRNOP00000059964 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | Similar to Ras GTPase-activating protein nGAP (RAS protein activator like 1) (Predicted). | 0.508 |
Acy3 | Sash3 | ENSRNOP00000024112 | ENSRNOP00000006035 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | Similar to RIKEN cDNA 1200013B08 (Predicted). | 0.510 |
Acy3 | Skp1 | ENSRNOP00000024112 | ENSRNOP00000073214 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] | 0.593 |
Acy3 | Susd3 | ENSRNOP00000024112 | ENSRNOP00000031097 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | Sushi domain containing 3 (Predicted), isoform CRA_c. | 0.510 |
Acy3 | Tbx10 | ENSRNOP00000024112 | ENSRNOP00000024129 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | T-box transcription factor 10. | 0.504 |
Agmat | Acy1 | ENSRNOP00000016646 | ENSRNOP00000015852 | Agmatinase, mitochondrial; Belongs to the arginase family. Agmatinase subfamily. | Aminoacylase-1A; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate). | 0.401 |
Agmat | Acy3 | ENSRNOP00000016646 | ENSRNOP00000024112 | Agmatinase, mitochondrial; Belongs to the arginase family. Agmatinase subfamily. | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | 0.475 |
Agmat | Noxred1 | ENSRNOP00000016646 | ENSRNOP00000065836 | Agmatinase, mitochondrial; Belongs to the arginase family. Agmatinase subfamily. | NADP-dependent oxidoreductase domain-containing 1. | 0.552 |
Aspa | Acy1 | ENSRNOP00000072876 | ENSRNOP00000015852 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | Aminoacylase-1A; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate). | 0.847 |
Aspa | Acy3 | ENSRNOP00000072876 | ENSRNOP00000024112 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | 0.613 |
Aspa | Skp1 | ENSRNOP00000072876 | ENSRNOP00000073214 | Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] | 0.602 |
Dhrs9 | Acy3 | ENSRNOP00000069708 | ENSRNOP00000024112 | Dehydrogenase/reductase SDR family member 9; 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha- tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone (By similarity). Plays also role in the biosynthesis of retinoic acid from retinaldehyde. Can utilize both NADH and NADPH (By similarity). Belongs to the short-chain dehydrogenases/reductases (SDR) family. | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids (By similarity); Belongs to the AspA/AstE family. Aspartoacylase subfamily. | 0.491 |