node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Agpat1 | Agpat2 | ENSRNOP00000000500 | ENSRNOP00000026408 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.909 |
Agpat1 | Agpat4 | ENSRNOP00000000500 | ENSRNOP00000069883 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity). | 0.976 |
Agpat1 | Agpat5 | ENSRNOP00000000500 | ENSRNOP00000037069 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 1-acylglycerol-3-phosphate O-acyltransferase 5. | 0.960 |
Agpat1 | Cds1 | ENSRNOP00000000500 | ENSRNOP00000002918 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Phosphatidate cytidylyltransferase 1; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells (By similarity). May play an important role in phosphoinositide synthesis, prefers 1- stearoyl-2-arachidonoyl phosphatidic acid as substrate; Belongs to the CDS family. | 0.954 |
Agpat1 | Cds2 | ENSRNOP00000000500 | ENSRNOP00000028888 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Phosphatidate cytidylyltransferase 2; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin; Belongs to the CDS family. | 0.954 |
Agpat1 | Mboat1 | ENSRNOP00000000500 | ENSRNOP00000034823 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Membrane-bound O-acyltransferase domain-containing 1; Belongs to the membrane-bound acyltransferase family. | 0.925 |
Agpat1 | Mboat2 | ENSRNOP00000000500 | ENSRNOP00000075292 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Membrane-bound O-acyltransferase domain-containing protein 2; Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. | 0.969 |
Agpat1 | Plpp4 | ENSRNOP00000000500 | ENSRNOP00000027681 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Phospholipid phosphatase 4. | 0.937 |
Agpat1 | Plpp5 | ENSRNOP00000000500 | ENSRNOP00000020900 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Phospholipid phosphatase 5. | 0.937 |
Agpat2 | Agpat1 | ENSRNOP00000026408 | ENSRNOP00000000500 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.909 |
Agpat2 | Agpat4 | ENSRNOP00000026408 | ENSRNOP00000069883 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity). | 0.961 |
Agpat2 | Agpat5 | ENSRNOP00000026408 | ENSRNOP00000037069 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 1-acylglycerol-3-phosphate O-acyltransferase 5. | 0.958 |
Agpat2 | Cds1 | ENSRNOP00000026408 | ENSRNOP00000002918 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Phosphatidate cytidylyltransferase 1; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells (By similarity). May play an important role in phosphoinositide synthesis, prefers 1- stearoyl-2-arachidonoyl phosphatidic acid as substrate; Belongs to the CDS family. | 0.954 |
Agpat2 | Cds2 | ENSRNOP00000026408 | ENSRNOP00000028888 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Phosphatidate cytidylyltransferase 2; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin; Belongs to the CDS family. | 0.954 |
Agpat2 | Mboat1 | ENSRNOP00000026408 | ENSRNOP00000034823 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Membrane-bound O-acyltransferase domain-containing 1; Belongs to the membrane-bound acyltransferase family. | 0.918 |
Agpat2 | Mboat2 | ENSRNOP00000026408 | ENSRNOP00000075292 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Membrane-bound O-acyltransferase domain-containing protein 2; Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. | 0.969 |
Agpat2 | Plpp4 | ENSRNOP00000026408 | ENSRNOP00000027681 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Phospholipid phosphatase 4. | 0.950 |
Agpat2 | Plpp5 | ENSRNOP00000026408 | ENSRNOP00000020900 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | Phospholipid phosphatase 5. | 0.939 |
Agpat4 | Agpat1 | ENSRNOP00000069883 | ENSRNOP00000000500 | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity). | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.976 |
Agpat4 | Agpat2 | ENSRNOP00000069883 | ENSRNOP00000026408 | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity). | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. | 0.961 |